Special Issue “Nature or Synthetic Compounds for Treating Arterial Thrombosis and Ischemic Stroke”

Thanasekaran Jayakumar, Joen Rong Sheu

Research output: Contribution to journalEditorialpeer-review


Stroke is the second main cause of mortality and morbidity globally. It has been estimated that approximately 80% of strokes are affected by focal cerebral ischemia due to arterial occlusion, while up to 20% are caused by intracerebral hemorrhages. In roughly one-third of ischemic stroke patients, embolism to the brain is caused by the heart, particularly atrial fibrillation. The thromboembolic occlusion of major or multiple smaller intracerebral arteries results in the focal impairment of the downstream blood flow and in secondary thrombus formation within the cerebral microvasculature. Research shows that it is necessary to employ exogenous natural drugs to counter cerebral ischemia. Currently, there are few effective neuroprotective agents that can be used for treating ischemic stroke. There have been abundant efforts taken to improve stroke outcome through the use of antiplatelet and anticoagulants. This Special Issue is intended to invite research as well as review papers concerning thromboembolic stroke treatment by using natural and synthetic compounds.
Original languageEnglish
Article number8194
JournalApplied Sciences (Switzerland)
Issue number16
Publication statusPublished - Aug 2022

ASJC Scopus subject areas

  • General Materials Science
  • Instrumentation
  • General Engineering
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes


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