TY - JOUR
T1 - Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet
AU - Chen, Jiun-Rong
AU - Liu, Shih Ming
AU - Yang, Suh-Ching
AU - Suetsuna, Kunio
PY - 2004/10
Y1 - 2004/10
N2 - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.
AB - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.
KW - cholesterol
KW - lipid metabolism
KW - rat
KW - soybean
KW - soymilk
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U2 - 10.1016/j.nut.2004.06.015
DO - 10.1016/j.nut.2004.06.015
M3 - Article
C2 - 15474884
AN - SCOPUS:4944227131
SN - 0899-9007
VL - 20
SP - 929
EP - 933
JO - Nutrition
JF - Nutrition
IS - 10
ER -
