Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

Jiun-Rong Chen; Shih Ming Liu; Suh-Ching Yang; Kunio Suetsuna

doi:10.1016/j.nut.2004.06.015

Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

Jiun-Rong Chen, Shih Ming Liu, Suh-Ching Yang, Kunio Suetsuna

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

Original language	English
Pages (from-to)	929-933
Number of pages	5
Journal	Nutrition
Volume	20
Issue number	10
DOIs	https://doi.org/10.1016/j.nut.2004.06.015
Publication status	Published - Oct 2004

Keywords

cholesterol
lipid metabolism
rat
soybean
soymilk

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Surgery
Medicine (miscellaneous)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.nut.2004.06.015

Cite this

@article{4768ff67a69e4b49b286f19008ae1199,

title = "Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet",

abstract = "Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.",

keywords = "cholesterol, lipid metabolism, rat, soybean, soymilk",

author = "Jiun-Rong Chen and Liu, {Shih Ming} and Suh-Ching Yang and Kunio Suetsuna",

year = "2004",

month = oct,

doi = "10.1016/j.nut.2004.06.015",

language = "English",

volume = "20",

pages = "929--933",

journal = "Nutrition",

issn = "0899-9007",

publisher = "Elsevier Inc.",

number = "10",

}

TY - JOUR

T1 - Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

AU - Chen, Jiun-Rong

AU - Liu, Shih Ming

AU - Yang, Suh-Ching

AU - Suetsuna, Kunio

PY - 2004/10

Y1 - 2004/10

N2 - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

AB - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

KW - cholesterol

KW - lipid metabolism

KW - rat

KW - soybean

KW - soymilk

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DO - 10.1016/j.nut.2004.06.015

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AN - SCOPUS:4944227131

SN - 0899-9007

VL - 20

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EP - 933

JO - Nutrition

JF - Nutrition

IS - 10

ER -

Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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