TY - JOUR
T1 - Sixteen years post radiotherapy of nasopharyngeal carcinoma elicited multi-dysfunction along PTX and chronic kidney disease with microcytic anemia
AU - Lin, Yi Ting
AU - Huang, Chia Chun
AU - Chyau, Charng Cherng
AU - Chen, Kuan Chou
AU - Peng, Robert Y.
PY - 2014/2/12
Y1 - 2014/2/12
N2 - Background: The hypothalamic-pituitary (h-p) unit is a particularly radiosensitive region in the central nervous system. As a consequence, radiation-induced irreversible, progressively chronic onset hypopituitarism (RIH) commonly develops after radiation treatments and can result in variably impaired pituitary function, which is frequently associated with increased morbidity and mortality. Case presentation. A 38-year-old male subject, previously having received radiotherapy for treatment of nasopharygeal carcinoma (NPCA) 16 years ago, appeared at OPD complaining about his failure in penile erection, loss of pubic hair, atrophy of external genitalia: testicles reduced to 2×1.5 cm; penile size shrunk to only 4 cm long. Characteristically, he showed extremely lowered human growth hormone, (HGH, 0.115 ng/mL), testosterone (
AB - Background: The hypothalamic-pituitary (h-p) unit is a particularly radiosensitive region in the central nervous system. As a consequence, radiation-induced irreversible, progressively chronic onset hypopituitarism (RIH) commonly develops after radiation treatments and can result in variably impaired pituitary function, which is frequently associated with increased morbidity and mortality. Case presentation. A 38-year-old male subject, previously having received radiotherapy for treatment of nasopharygeal carcinoma (NPCA) 16 years ago, appeared at OPD complaining about his failure in penile erection, loss of pubic hair, atrophy of external genitalia: testicles reduced to 2×1.5 cm; penile size shrunk to only 4 cm long. Characteristically, he showed extremely lowered human growth hormone, (HGH, 0.115 ng/mL), testosterone (
KW - Adrenal insufficiency
KW - Chronic kidney disease
KW - Hypogonadism
KW - Hypopituitarism
KW - Hypothyroidism
KW - Microcytic anemia
KW - Radiotherapy
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U2 - 10.1186/1471-2490-14-19
DO - 10.1186/1471-2490-14-19
M3 - Article
C2 - 24520983
AN - SCOPUS:84896708696
SN - 1471-2490
VL - 14
JO - BMC Urology
JF - BMC Urology
IS - 1
M1 - 19
ER -