Abstract
We have measured serum TNF-α levels in 220 gastric cancer patients, 9 patients with gastric polyps or ulcers, 9 hepatitis B carriers and 85 normal controls. The results showed that no postitive TNF-α value ( > 10 pg/ml) was detected in Hepatitis B carriers and benign gastric lesions' patients and normal controls. In the cancer group, 17 out of 220 patients (7.7%) had positive-TNF-α values. The proportion of TNF-α positive was 6.8% in stage I disease, 6.5% in stage ll disease, 3.7% stage III, and 12.9% stage IV. No clinicopathologic factors were related to positive TNF-α value. TNF-α value was not an indenendent prognostic indicator. The role of TNF-α in gastric cancer remains obscures.
Original language | English |
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Pages (from-to) | 1597-1599 |
Number of pages | 3 |
Journal | Anticancer Research |
Volume | 18 |
Issue number | 3 A |
Publication status | Published - May 1998 |
Keywords
- Gastric cancer
- TNF-α
ASJC Scopus subject areas
- Cancer Research
- Oncology