Serial MRI studies in pathologically verified Balo's concentric sclerosis

Chi Jen Chen, Long Sun Ro, Chen Nen Chang, Yat Sen Ho, Chin Song Lu

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


We report serial MRI studies in a patient with Balo's concentric sclerosis, who presented with a progressive weakness in the right limbs of 10 day duration. Serial MR images revealed several concentric lesions characterized by layer by layer of demyelinated and myelinated appearance and multiple plaques in the white matter. Pathological study of a biopsy of a concentric lesion (which was performed to rule out neoplasm) further confirmed this diagnosis. These MR findings resolved in correspondence with clinical improvement. The patient was almost completely normal 1 year later. In conclusion, in this case, we found that MRI could show the striking feature reminiscent of the histopathologic findings of Balo's concentric sclerosis and played an important role in antemortem diagnosis of this rare demyelinating disease.

Original languageEnglish
Pages (from-to)732-735
Number of pages4
JournalJournal of Computer Assisted Tomography
Issue number5
Publication statusPublished - 1996
Externally publishedYes


  • Brain, demyelination
  • Brain, diseases
  • Central nervous system, diseases
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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