Segregated neural representation of distinct emotion dimensions in the prefrontal cortex - An fMRI study

Simone Grimm; Conny F. Schmidt; Felix Bermpohl; Alexander Heinzel; Yuliya Dahlem; Michael Wyss; Daniel Hell; Peter Boesiger; Heinz Boeker; Georg Northoff

doi:10.1016/j.neuroimage.2005.09.006

Segregated neural representation of distinct emotion dimensions in the prefrontal cortex - An fMRI study

Simone Grimm, Conny F. Schmidt, Felix Bermpohl, Alexander Heinzel, Yuliya Dahlem, Michael Wyss, Daniel Hell, Peter Boesiger, Heinz Boeker, Georg Northoff

Research output: Contribution to journal › Article › peer-review

160 Citations (Scopus)

Abstract

Emotions are frequently characterized by distinct dimensions such as valence, intensity, and recognition. However, the exact neural representation of these dimensions in different prefrontal cortical regions remains unclear. One of the problems in revealing prefrontal cortical representation is that the very same regions are also involved in cognitive functions associated with emotion processing. We therefore conducted an fMRI study involving the viewing of emotional pictures (using the International Affective Picture System; IAPS) and controlled for associated cognitive processing like judgment and preceding attention. Functional activation was correlated with subjective post-scanning ratings of valence, intensity, and recognition. Valence significantly correlated with the functional response in ventromedial prefrontal cortex (VMPFC) and dorsolateral prefrontal cortex (DLPFC), intensity with activation in ventrolateral prefrontal cortex (VLPFC) and dorsomedial prefrontal cortex (DMPFC), and recognition with the functional response in perigenual anterior cingulate cortex (PACC). In conclusion, our results indicate segregated neural representation of the different emotion dimensions in different prefrontal cortical regions.

Original language	English
Pages (from-to)	325-340
Number of pages	16
Journal	NeuroImage
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/j.neuroimage.2005.09.006
Publication status	Published - Mar 2006

Keywords

Emotions
Expectancy
fMRI
Judgment
Prefrontal cortex
Valence

ASJC Scopus subject areas

Cognitive Neuroscience
Neurology

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10.1016/j.neuroimage.2005.09.006

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title = "Segregated neural representation of distinct emotion dimensions in the prefrontal cortex - An fMRI study",

abstract = "Emotions are frequently characterized by distinct dimensions such as valence, intensity, and recognition. However, the exact neural representation of these dimensions in different prefrontal cortical regions remains unclear. One of the problems in revealing prefrontal cortical representation is that the very same regions are also involved in cognitive functions associated with emotion processing. We therefore conducted an fMRI study involving the viewing of emotional pictures (using the International Affective Picture System; IAPS) and controlled for associated cognitive processing like judgment and preceding attention. Functional activation was correlated with subjective post-scanning ratings of valence, intensity, and recognition. Valence significantly correlated with the functional response in ventromedial prefrontal cortex (VMPFC) and dorsolateral prefrontal cortex (DLPFC), intensity with activation in ventrolateral prefrontal cortex (VLPFC) and dorsomedial prefrontal cortex (DMPFC), and recognition with the functional response in perigenual anterior cingulate cortex (PACC). In conclusion, our results indicate segregated neural representation of the different emotion dimensions in different prefrontal cortical regions.",

keywords = "Emotions, Expectancy, fMRI, Judgment, Prefrontal cortex, Valence",

author = "Simone Grimm and Schmidt, {Conny F.} and Felix Bermpohl and Alexander Heinzel and Yuliya Dahlem and Michael Wyss and Daniel Hell and Peter Boesiger and Heinz Boeker and Georg Northoff",

note = "Funding Information: The study was supported by a Heisenberg grant from the German Research Foundation (DFG, 304/4–1 to G.N.), a grant within the Postdoc-Programme of the German Academic Exchange Service (DAAD, D/02/46858) to F.B, the Swiss National Research Foundation (3100A0-100830) to G.N. and H.B., a grant from the Research Foundation of the University of Zurich, Organon Switzerland to G.N. and H.B., and a grant from ETH Zurich (SEP) and Philips Medical Systems, Best, NL, to P.B.",

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AU - Grimm, Simone

AU - Schmidt, Conny F.

AU - Bermpohl, Felix

AU - Heinzel, Alexander

AU - Dahlem, Yuliya

AU - Wyss, Michael

AU - Hell, Daniel

AU - Boesiger, Peter

AU - Boeker, Heinz

AU - Northoff, Georg

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PY - 2006/3

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N2 - Emotions are frequently characterized by distinct dimensions such as valence, intensity, and recognition. However, the exact neural representation of these dimensions in different prefrontal cortical regions remains unclear. One of the problems in revealing prefrontal cortical representation is that the very same regions are also involved in cognitive functions associated with emotion processing. We therefore conducted an fMRI study involving the viewing of emotional pictures (using the International Affective Picture System; IAPS) and controlled for associated cognitive processing like judgment and preceding attention. Functional activation was correlated with subjective post-scanning ratings of valence, intensity, and recognition. Valence significantly correlated with the functional response in ventromedial prefrontal cortex (VMPFC) and dorsolateral prefrontal cortex (DLPFC), intensity with activation in ventrolateral prefrontal cortex (VLPFC) and dorsomedial prefrontal cortex (DMPFC), and recognition with the functional response in perigenual anterior cingulate cortex (PACC). In conclusion, our results indicate segregated neural representation of the different emotion dimensions in different prefrontal cortical regions.

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Segregated neural representation of distinct emotion dimensions in the prefrontal cortex - An fMRI study

Abstract

Keywords

ASJC Scopus subject areas

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