Secretory carcinoma: A silent mass increasing in the Parotid gland

Cheng Chieh Lu; Chien Jui Cheng; Yu Chien Kao; Mei Chien Chen

doi:10.3889/oamjms.2020.4603

Secretory carcinoma: A silent mass increasing in the Parotid gland

Cheng Chieh Lu, Chien Jui Cheng, Yu Chien Kao, Mei Chien Chen

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene. CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses. CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.

Original language	English
Pages (from-to)	191-194
Number of pages	4
Journal	Open Access Macedonian Journal of Medical Sciences
Volume	8
Issue number	C
DOIs	https://doi.org/10.3889/oamjms.2020.4603
Publication status	Published - Jan 2 2020

Keywords

Mammary analog secretory carcinoma
Salivary gland cancer
Salivary gland neoplasms
Secretory carcinoma

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3889/oamjms.2020.4603

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title = "Secretory carcinoma: A silent mass increasing in the Parotid gland",

abstract = "BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene. CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses. CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.",

keywords = "Mammary analog secretory carcinoma, Salivary gland cancer, Salivary gland neoplasms, Secretory carcinoma",

author = "Lu, {Cheng Chieh} and Cheng, {Chien Jui} and Kao, {Yu Chien} and Chen, {Mei Chien}",

note = "Funding Information: The paper had complied with the guidelines for human studies and animal welfare regulations. The authors state that subjects have given their informed consent and that the study protocol has been approved by the Institute?s Committee on Human Research (TMUJIRB number: N201812013). The authors also state that animal experiments conform to institutional standards. Publisher Copyright: {\textcopyright} 2020 Cheng-Chieh Lu, Chien-Jui Cheng, Yu-Chien Kao, Mei-Chien Chen.",

year = "2020",

month = jan,

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doi = "10.3889/oamjms.2020.4603",

language = "English",

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T2 - A silent mass increasing in the Parotid gland

AU - Lu, Cheng Chieh

AU - Cheng, Chien Jui

AU - Kao, Yu Chien

AU - Chen, Mei Chien

N1 - Funding Information: The paper had complied with the guidelines for human studies and animal welfare regulations. The authors state that subjects have given their informed consent and that the study protocol has been approved by the Institute?s Committee on Human Research (TMUJIRB number: N201812013). The authors also state that animal experiments conform to institutional standards. Publisher Copyright: © 2020 Cheng-Chieh Lu, Chien-Jui Cheng, Yu-Chien Kao, Mei-Chien Chen.

PY - 2020/1/2

Y1 - 2020/1/2

N2 - BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene. CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses. CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.

AB - BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene. CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses. CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.

KW - Mammary analog secretory carcinoma

KW - Salivary gland cancer

KW - Salivary gland neoplasms

KW - Secretory carcinoma

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JO - Open Access Macedonian Journal of Medical Sciences

JF - Open Access Macedonian Journal of Medical Sciences

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Secretory carcinoma: A silent mass increasing in the Parotid gland

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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