Abstract
Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.
Original language | English |
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Pages (from-to) | 296-299 |
Number of pages | 4 |
Journal | Journal of Microbiology, Immunology and Infection |
Volume | 38 |
Issue number | 4 |
Publication status | Published - Aug 2005 |
Externally published | Yes |
Keywords
- Heart block
- Ribonuclearprotein antigen
- SS-A antibodies
- Systemic lupus erythematosus
ASJC Scopus subject areas
- General Immunology and Microbiology
- Microbiology (medical)
- Infectious Diseases
- Immunology and Allergy