Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo; Kang Cheng Su; Hsien Tzung Liao; Chung Tei Chou; Hsiao Ning Chang

Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo, Kang Cheng Su, Hsien Tzung Liao, Chung Tei Chou, Hsiao Ning Chang

Research output: Contribution to journal › Article › peer-review

Abstract

Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

Original language	English
Pages (from-to)	296-299
Number of pages	4
Journal	Journal of Microbiology, Immunology and Infection
Volume	38
Issue number	4
Publication status	Published - Aug 2005
Externally published	Yes

Keywords

Heart block
Ribonuclearprotein antigen
SS-A antibodies
Systemic lupus erythematosus

ASJC Scopus subject areas

General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
Immunology and Allergy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus",

abstract = "Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sj{\"o}gren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.",

keywords = "Heart block, Ribonuclearprotein antigen, SS-A antibodies, Systemic lupus erythematosus",

author = "Huo, {An Ping} and Su, {Kang Cheng} and Liao, {Hsien Tzung} and Chou, {Chung Tei} and Chang, {Hsiao Ning}",

year = "2005",

month = aug,

language = "English",

volume = "38",

pages = "296--299",

journal = "Journal of Microbiology, Immunology and Infection",

issn = "1684-1182",

publisher = "Lippincott Williams & Wilkins Asia",

number = "4",

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TY - JOUR

T1 - Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

AU - Huo, An Ping

AU - Su, Kang Cheng

AU - Liao, Hsien Tzung

AU - Chou, Chung Tei

AU - Chang, Hsiao Ning

PY - 2005/8

Y1 - 2005/8

N2 - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

AB - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

KW - Heart block

KW - Ribonuclearprotein antigen

KW - SS-A antibodies

KW - Systemic lupus erythematosus

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SN - 1684-1182

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JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

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ER -

Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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