Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo; Kang Cheng Su; Hsien Tzung Liao; Chung Tei Chou; Hsiao Ning Chang

Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo, Kang Cheng Su, Hsien Tzung Liao, Chung Tei Chou, Hsiao Ning Chang

Research output: Contribution to journal › Article › peer-review

Abstract

Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

Original language	English
Pages (from-to)	296-299
Number of pages	4
Journal	Journal of Microbiology, Immunology and Infection
Volume	38
Issue number	4
Publication status	Published - Aug 2005
Externally published	Yes

Keywords

Heart block
Ribonuclearprotein antigen
SS-A antibodies
Systemic lupus erythematosus

ASJC Scopus subject areas

Microbiology (medical)
Immunology and Allergy
Immunology and Microbiology(all)

Cite this

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title = "Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus",

abstract = "Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sj{\"o}gren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.",

keywords = "Heart block, Ribonuclearprotein antigen, SS-A antibodies, Systemic lupus erythematosus",

author = "Huo, {An Ping} and Su, {Kang Cheng} and Liao, {Hsien Tzung} and Chou, {Chung Tei} and Chang, {Hsiao Ning}",

year = "2005",

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journal = "Journal of Microbiology, Immunology and Infection",

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T1 - Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

AU - Huo, An Ping

AU - Su, Kang Cheng

AU - Liao, Hsien Tzung

AU - Chou, Chung Tei

AU - Chang, Hsiao Ning

PY - 2005/8

Y1 - 2005/8

N2 - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

AB - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

KW - Heart block

KW - Ribonuclearprotein antigen

KW - SS-A antibodies

KW - Systemic lupus erythematosus

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Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

Abstract

Keywords

ASJC Scopus subject areas

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