Rutaecarpine, an alkaloid from evodia rutaecarpa, can prevent platelet activation in humans and reduce microvascular thrombosis in mice: crucial role of the pi3k/akt/gsk3β signal axis through a cyclic nucleotides/vasp—independent mechanism

Chun Jen Huang, Wei Chieh Huang, Wei Ting Lin, Lan Hsin Shu, Joen Rong Sheu, Oanh Thi Tran, Chih Wei Hsia, Thanasekaran Jayakumar, Periyakali Saravana Bhavan, Cheng Ying Hsieh, Chao Chien Chang

TMU Research Center of Cancer Translational Medicine
TMU Research Center of Cell Therapy and Regeneration Medicine
Taipei Municipal Wanfang Hospital
Department of Anesthesiology
Graduate Institute of Clinical Medicine
Graduate Institute of Medical Sciences
Graduate Institute of Metabolism and Obesity Sciences
International Master/Ph.D. Program in Medicine
TMU Research Center of Neuroscience
Ph.D. Program in Medical Neuroscience
The Ph.D. Program for Translational Medicine
Department of Pharmacology
Taipei Medical University Hospital
School of Nutrition and Health Sciences
Division of Gastroenterology and Hepatology
TMU Research Center for Digestive Medicine

Research output: Contribution to journal › Article › peer-review

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Rutaecarpine, an alkaloid from evodia rutaecarpa, can prevent platelet activation in humans and reduce microvascular thrombosis in mice: crucial role of the pi3k/akt/gsk3β signal axis through a cyclic nucleotides/vasp—independent mechanism

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science