Risk stratification and clinical outcomes in patients with acute pulmonary embolism

Chi Ming Huang, Yen Chung Lin, Yenn Jiang Lin, Shih Lin Chang, Li Wei Lo, Yu Feng Hu, Chern En Chiang, Kang Ling Wang, Shih Ann Chen

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Objectives: Pulmonary embolism is a common disease associated with a high mortality rate. The risk assessment and appropriate treatment selection of patients with acute pulmonary embolism remains a challenge. Design and methods: This single center cohort study included a total of 150 patients (96 male, age = 71. ±. 15 years) with acute pulmonary embolism confirmed by spiral-computed tomography or magnetic resonance image. The prognostic performance of the clinical characteristics and laboratory values were investigated to predict the in-hospital hemodynamically instable events and 30-day all-cause mortality. Results: The rate of in-hospital hemodynamic instability and 30-day all-cause mortality was 21% and 12%, respectively. A multivariate Cox regression analysis demonstrated that a heart rate≥ 110bpm (odd ratio 4.26 [95% CI 1.42-12.77]), chronic pulmonary disease (6.47 [1.99-21.04]), WBC≥11,000mm 3 (3.78 [1.32-10.82]), and D-dimer level≥4.0μg/mL (3.68 [1.01-13.43]) independently predicted the 30-day fatal outcome. A Kaplan-Meier survival analysis showed that the categorization based on the number of risk factors was significantly associated with the likelihood of 30-day all-cause mortality (P

Original languageEnglish
Pages (from-to)1110-1115
Number of pages6
JournalClinical Biochemistry
Issue number13
Publication statusPublished - Sept 2011


  • Hemodynamic instability
  • Mortality
  • Prognosis
  • Pulmonary embolism
  • Risk stratification

ASJC Scopus subject areas

  • Clinical Biochemistry


Dive into the research topics of 'Risk stratification and clinical outcomes in patients with acute pulmonary embolism'. Together they form a unique fingerprint.

Cite this