Risk of second primary malignancies after nasopharyngeal carcinoma: A population-based cohort study in Taiwan

Charlene Lin; Shih Wei Lin; Shih Feng Weng; Yong-Song Lin

doi:10.1002/hed.23281

Risk of second primary malignancies after nasopharyngeal carcinoma: A population-based cohort study in Taiwan

Charlene Lin, Shih Wei Lin, Shih Feng Weng, Yong-Song Lin

Department of Otolaryngology

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Background The purpose of this study was to examine the risk of second primary malignancy (SPM) after nasopharyngeal carcinoma (NPC). Methods We compared the incidence of SPM in patients diagnosed with NPC at the end of 2009 using the data extracted from the Taiwan Longitudinal Health Insurance Database between 2001 and 2008 (n = 10,299), with age-matched controls (1:10; n = 102,990). Results We found a 55% increased risk of SPM in patients diagnosed with NPC, compared to the risk of first malignancy in the age-matched controls (incidence rate ratio [IRR] = 1.55; p

Original language	English
Pages (from-to)	209-214
Number of pages	6
Journal	Head and Neck
Volume	36
Issue number	2
DOIs	https://doi.org/10.1002/hed.23281
Publication status	Published - Feb 2014

Keywords

cancer survival
nasopharyngeal carcinoma
oral cancer
oropharyngeal carcinoma
second primary malignancy

ASJC Scopus subject areas

Otorhinolaryngology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/hed.23281

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title = "Risk of second primary malignancies after nasopharyngeal carcinoma: A population-based cohort study in Taiwan",

abstract = "Background The purpose of this study was to examine the risk of second primary malignancy (SPM) after nasopharyngeal carcinoma (NPC). Methods We compared the incidence of SPM in patients diagnosed with NPC at the end of 2009 using the data extracted from the Taiwan Longitudinal Health Insurance Database between 2001 and 2008 (n = 10,299), with age-matched controls (1:10; n = 102,990). Results We found a 55% increased risk of SPM in patients diagnosed with NPC, compared to the risk of first malignancy in the age-matched controls (incidence rate ratio [IRR] = 1.55; p ",

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T1 - Risk of second primary malignancies after nasopharyngeal carcinoma

T2 - A population-based cohort study in Taiwan

AU - Lin, Charlene

AU - Lin, Shih Wei

AU - Weng, Shih Feng

AU - Lin, Yong-Song

PY - 2014/2

Y1 - 2014/2

N2 - Background The purpose of this study was to examine the risk of second primary malignancy (SPM) after nasopharyngeal carcinoma (NPC). Methods We compared the incidence of SPM in patients diagnosed with NPC at the end of 2009 using the data extracted from the Taiwan Longitudinal Health Insurance Database between 2001 and 2008 (n = 10,299), with age-matched controls (1:10; n = 102,990). Results We found a 55% increased risk of SPM in patients diagnosed with NPC, compared to the risk of first malignancy in the age-matched controls (incidence rate ratio [IRR] = 1.55; p

AB - Background The purpose of this study was to examine the risk of second primary malignancy (SPM) after nasopharyngeal carcinoma (NPC). Methods We compared the incidence of SPM in patients diagnosed with NPC at the end of 2009 using the data extracted from the Taiwan Longitudinal Health Insurance Database between 2001 and 2008 (n = 10,299), with age-matched controls (1:10; n = 102,990). Results We found a 55% increased risk of SPM in patients diagnosed with NPC, compared to the risk of first malignancy in the age-matched controls (incidence rate ratio [IRR] = 1.55; p

KW - cancer survival

KW - nasopharyngeal carcinoma

KW - oral cancer

KW - oropharyngeal carcinoma

KW - second primary malignancy

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Risk of second primary malignancies after nasopharyngeal carcinoma: A population-based cohort study in Taiwan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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