Risk of accidental injuries amongst Parkinson disease patients

Han-Cheng Wang, C. C. Lin, C. I. Lau, A. Chang, F. C. Sung, C. H. Kao

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Background and purpose: To investigate the spectrum and risks of accidental injuries (AIs) amongst Parkinson disease (PD) patients. Methods: The participants comprised PD patients aged 50 years and older who were initially diagnosed between 2000 and 2009, and a comparison group of non-PD patients. The incidence rates of accidental injury types amongst PD and non-PD patients were calculated; hazard ratios were calculated and adjusted for comorbidities, using 95% confidence intervals (CIs) of developing such outcomes in PD patients. Results: In total, 4046 PD patients and 16 184 non-PD patients were followed over time. The PD patients demonstrated the following incidence rates and hazard ratios in comparison to the control cohort for accidental injuries: all injuries, 19.78 per 100 person-years (100 PYs), adjusted hazard ratio (HR) 1.30 (95% CI 1.24-1.36); head injury, 2.95 per 100 PYs, HR 1.88 (95% CI 1.64-2.15); bone fracture and dislocation, 4.61 per 100 PYs, HR 1.39 (95% CI 1.25-1.54); burns, 0.66 per 100 PYs, HR 1.01 (95% CI 0.78-1.32); injury to spinal cord, plexus and nerves, 0.15 per 100 PYs, HR 1.25 (95% CI 0.72-2.17); superficial injuries and contusions, 11.41 per 100 PYs, HR 1.20 (95% CI 1.12-1.27). The injury risk for the 69-79 years age group in PD compared with controls of the same age (HR 1.38) was significantly higher compared with that of the 50-69 age groups in PD and controls (HR 1.16). Conclusions: Parkinson disease patients demonstrate a significantly elevated risk of developing all accidental injury types except burn injuries and injuries to spinal cord, plexus and nerves, compared with age-matched controls. The risk increases as age increases.

Original languageEnglish
Pages (from-to)907-913
Number of pages7
JournalEuropean Journal of Neurology
Issue number6
Publication statusPublished - 2014


  • Accidental injuries
  • National Health Insurance Research Database (NHIRD)
  • Parkinson disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)


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