TY - JOUR
T1 - Risk factors for recurrent hypoglycemia in hospitalized diabetic patients admitted for severe hypoglycemia
AU - Lin, Yen Yue
AU - Hsu, Chin Wang
AU - Sheu, Wayne Huey Herng
AU - Chu, Shi Jye
AU - Wu, Chin Pyng
AU - Tsai, Shih Hung
PY - 2010/5
Y1 - 2010/5
N2 - Purpose: Severe hypoglycemia can result in neural damage, impaired cognitive function, coma, seizures, or death. The decision to admit diabetic patients after initial treatment in the emergency department remains unclear. Our purpose is to identify risk factors for developing recurrent hypoglycemia in diabetic patients admitted for severe hypoglycemia. Materials and Methods: We reviewed the records of 233 subjects (92 males, 141 females; mean age, 74.1 ± 9.8 years) with type 2 diabetes treated at a tertiary care teaching hospital and hospitalized for severe hypoglycemia. Results: Seventy-four (31.8%) patients were categorized with recurrent hypoglycemia and 159 (68.2%) with non-recurrent. Multivariate logistic regression analysis revealed that patients with loss of a recent meal, coronary artery disease, infection, and poor renal function (lower estimated glomerular filtration rate) were at risk for recurrent hypoglycemia. The use of calcium-channel blockers appeared to be a protective factor for the development of recurrent hypoglycemia. Conclusion: There may be a subset of patients with severe hypoglycemia and certain risk factors for recurrent hypoglycemia that should be admitted.
AB - Purpose: Severe hypoglycemia can result in neural damage, impaired cognitive function, coma, seizures, or death. The decision to admit diabetic patients after initial treatment in the emergency department remains unclear. Our purpose is to identify risk factors for developing recurrent hypoglycemia in diabetic patients admitted for severe hypoglycemia. Materials and Methods: We reviewed the records of 233 subjects (92 males, 141 females; mean age, 74.1 ± 9.8 years) with type 2 diabetes treated at a tertiary care teaching hospital and hospitalized for severe hypoglycemia. Results: Seventy-four (31.8%) patients were categorized with recurrent hypoglycemia and 159 (68.2%) with non-recurrent. Multivariate logistic regression analysis revealed that patients with loss of a recent meal, coronary artery disease, infection, and poor renal function (lower estimated glomerular filtration rate) were at risk for recurrent hypoglycemia. The use of calcium-channel blockers appeared to be a protective factor for the development of recurrent hypoglycemia. Conclusion: There may be a subset of patients with severe hypoglycemia and certain risk factors for recurrent hypoglycemia that should be admitted.
KW - Calcium channel blockers
KW - Chronic kidney disease
KW - Coronary artery disease
KW - Diabetic complications
KW - Hypoglycemia
KW - Mellitus
KW - Type 2 diabetes
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U2 - 10.3349/ymj.2010.51.3.367
DO - 10.3349/ymj.2010.51.3.367
M3 - Review article
C2 - 20376889
AN - SCOPUS:77954248624
SN - 0513-5796
VL - 51
SP - 367
EP - 374
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
IS - 3
ER -