TY - JOUR
T1 - Risk Factors for HIV-1 seroconversion among Taiwanese men visiting gay saunas who have sex with men
AU - Chen, Yen Ju
AU - Lin, Yu Ting
AU - Chen, Marcelo
AU - Huang, Szu Wei
AU - Lai, Su Fen
AU - Wong, Wing Wai
AU - Tsai, Hung Chin
AU - Lin, Yu Huei
AU - Liu, Hsin Fu
AU - Lyu, Shu Yu
AU - Chen, Yi Ming A
N1 - Funding Information:
We thank the MSM who participated in this study, and peer educators and social workers from the Living with Hope Organization for their help in collecting the questionnaires, and staff of the AIDS Prevention and Research Center of National Yang-Ming University for their administrative support and technical assistance. The authors also acknowledge the technical support provided by the Sequencing Core Facility of National Yang-Ming University’s Genome Research Center (YMGC). The Sequencing Core Facility is supported by the National Research Program for Genomic Medicine (NRPGM) of the National Science Council. This study was supported in part by the Centers for Disease Control of Taiwan (DOH92-DC-1034, DOH93-DC-1017, and DOH94-DC-1032). Parts of this paper were presented at the XV International Conference on AIDS held in Thailand and the 7th TPE AIDS Conference in 2004.
PY - 2011/12/5
Y1 - 2011/12/5
N2 - Background: Men having sex with men (MSM) accounts for 33.6% of all reported cases of HIV-1 infection in Taiwan. The aim of this study was to investigate the epidemiology of HIV-1 infection among MSM in gay saunas in Taiwan.Methods: Patrons of 5 gay saunas were recruited for a weekly volunteer counseling and testing program from 2001 to 2005. Questionnaires were collected for a risk factor analysis. HIV-1 subtypes were determined using DNA sequencing and phylogenetic analyses.Results: HIV-1 prevalence rates among MSM in gay saunas in 2001 through 2005 were 3.4%, 5.1%, 8.9%, 8.5%, and 8.3%, respectively. In total, 81 of 1, 093 (7.4%) MSM had HIV-1 infection. Fifty-two HIV-1 strains were genotyped, and all of them were subtype B. HIV-seropositive men were significantly younger than the seronegatives. Only 37.1% used condoms every time during sexual intercourse. A multivariate logistic regression analysis showed that the risk factors for HIV-1 were being uncircumcised (odds ratio (OR) = 2.19; 95% confidence interval (CI), 1.08~4.45); having sexual intercourse with at least 2 partners during each sauna visit (≥ 2 vs. ≤ 1, OR = 1.71; 95% CI, 1.02~2.89); and the role played during anal intercourse (versatile vs. an exclusively insertive role, OR = 2.76; 95% CI, 1.42~5.36).Conclusions: Overall, 7.4% Taiwanese MSM participating in this study had HIV-1 subtype B infection. Uncircumcised, being versatile role during anal intercourse, and having sex with more than one person during each sauna visit were main risk factors for HIV-1 infection.
AB - Background: Men having sex with men (MSM) accounts for 33.6% of all reported cases of HIV-1 infection in Taiwan. The aim of this study was to investigate the epidemiology of HIV-1 infection among MSM in gay saunas in Taiwan.Methods: Patrons of 5 gay saunas were recruited for a weekly volunteer counseling and testing program from 2001 to 2005. Questionnaires were collected for a risk factor analysis. HIV-1 subtypes were determined using DNA sequencing and phylogenetic analyses.Results: HIV-1 prevalence rates among MSM in gay saunas in 2001 through 2005 were 3.4%, 5.1%, 8.9%, 8.5%, and 8.3%, respectively. In total, 81 of 1, 093 (7.4%) MSM had HIV-1 infection. Fifty-two HIV-1 strains were genotyped, and all of them were subtype B. HIV-seropositive men were significantly younger than the seronegatives. Only 37.1% used condoms every time during sexual intercourse. A multivariate logistic regression analysis showed that the risk factors for HIV-1 were being uncircumcised (odds ratio (OR) = 2.19; 95% confidence interval (CI), 1.08~4.45); having sexual intercourse with at least 2 partners during each sauna visit (≥ 2 vs. ≤ 1, OR = 1.71; 95% CI, 1.02~2.89); and the role played during anal intercourse (versatile vs. an exclusively insertive role, OR = 2.76; 95% CI, 1.42~5.36).Conclusions: Overall, 7.4% Taiwanese MSM participating in this study had HIV-1 subtype B infection. Uncircumcised, being versatile role during anal intercourse, and having sex with more than one person during each sauna visit were main risk factors for HIV-1 infection.
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U2 - 10.1186/1471-2334-11-334
DO - 10.1186/1471-2334-11-334
M3 - Article
C2 - 22136602
AN - SCOPUS:82655170597
SN - 1471-2334
VL - 11
JO - BMC Infectious Diseases
JF - BMC Infectious Diseases
M1 - 334
ER -
