TY - JOUR
T1 - Risk factors and management of intra-abdominal infection after extended radical gastrectomy
AU - Lo, Chih Hsien
AU - Chen, Jen Hao
AU - Wu, Chew Wun
AU - Lo, Su Shun
AU - Hsieh, Mao Chih
AU - Lui, Wing Yiu
PY - 2008/11
Y1 - 2008/11
N2 - Background: This study elucidated risk factors and management for intra-abdominal infection after extended radical gastrectomy. Methods: From 1988 to 2004, 2,076 patients with gastric cancer underwent extended radical gastrectomy at Taipei Veterans General Hospital. Risk factors for intra-abdominal infection were determined by analyzing clinicopathological factors, operative procedure, combined organ resection, operative time, blood loss, and associated disease(s). Management modalities were summarized. Results: The overall complication rate was 18.7%. Eighty (3.9%) patients were found to have intra-abdominal infections. Age, prolonged operation time, and combined organ resection were the precipitating factors. These patients were categorized into 3 groups: intra-abdominal abscess with adequate drainage, intra-abdominal abscess without anastomotic leakage, and intra-abdominal abscess because of leakage. Adequate drainage was the primary treatment. Mortality rate was 22.5% (18), and the most common cause of mortality was intra-abdominal abscess caused by leakage. Conclusions: Although expert surgical skills can minimize the incidence of intra-abdominal infection, management also requires experience and training.
AB - Background: This study elucidated risk factors and management for intra-abdominal infection after extended radical gastrectomy. Methods: From 1988 to 2004, 2,076 patients with gastric cancer underwent extended radical gastrectomy at Taipei Veterans General Hospital. Risk factors for intra-abdominal infection were determined by analyzing clinicopathological factors, operative procedure, combined organ resection, operative time, blood loss, and associated disease(s). Management modalities were summarized. Results: The overall complication rate was 18.7%. Eighty (3.9%) patients were found to have intra-abdominal infections. Age, prolonged operation time, and combined organ resection were the precipitating factors. These patients were categorized into 3 groups: intra-abdominal abscess with adequate drainage, intra-abdominal abscess without anastomotic leakage, and intra-abdominal abscess because of leakage. Adequate drainage was the primary treatment. Mortality rate was 22.5% (18), and the most common cause of mortality was intra-abdominal abscess caused by leakage. Conclusions: Although expert surgical skills can minimize the incidence of intra-abdominal infection, management also requires experience and training.
KW - Complications
KW - Extended radical gastrectomy
KW - Gastric cancer
KW - Intra-abdominal infection
KW - Risk factors
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U2 - 10.1016/j.amjsurg.2007.11.031
DO - 10.1016/j.amjsurg.2007.11.031
M3 - Article
C2 - 18954604
AN - SCOPUS:54049150437
SN - 0002-9610
VL - 196
SP - 741
EP - 745
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 5
ER -