Risk factors and management of intra-abdominal infection after extended radical gastrectomy

Chih Hsien Lo, Jen Hao Chen, Chew Wun Wu, Su Shun Lo, Mao Chih Hsieh, Wing Yiu Lui

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Background: This study elucidated risk factors and management for intra-abdominal infection after extended radical gastrectomy. Methods: From 1988 to 2004, 2,076 patients with gastric cancer underwent extended radical gastrectomy at Taipei Veterans General Hospital. Risk factors for intra-abdominal infection were determined by analyzing clinicopathological factors, operative procedure, combined organ resection, operative time, blood loss, and associated disease(s). Management modalities were summarized. Results: The overall complication rate was 18.7%. Eighty (3.9%) patients were found to have intra-abdominal infections. Age, prolonged operation time, and combined organ resection were the precipitating factors. These patients were categorized into 3 groups: intra-abdominal abscess with adequate drainage, intra-abdominal abscess without anastomotic leakage, and intra-abdominal abscess because of leakage. Adequate drainage was the primary treatment. Mortality rate was 22.5% (18), and the most common cause of mortality was intra-abdominal abscess caused by leakage. Conclusions: Although expert surgical skills can minimize the incidence of intra-abdominal infection, management also requires experience and training.

Original languageEnglish
Pages (from-to)741-745
Number of pages5
JournalAmerican Journal of Surgery
Issue number5
Publication statusPublished - Nov 2008
Externally publishedYes


  • Complications
  • Extended radical gastrectomy
  • Gastric cancer
  • Intra-abdominal infection
  • Risk factors

ASJC Scopus subject areas

  • Surgery


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