Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: A case-control study

M. S. Lin; Y. S. Dai; R. F. Pwu; Y. H. Chen; Nen Chung Chang

doi:10.1111/j.1445-5994.2005.00790.x

Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: A case-control study

M. S. Lin, Y. S. Dai, R. F. Pwu, Y. H. Chen, Nen Chung Chang

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by multivariate analysis. The analysis was based on 35 cases and 105 controls. This study showed that the use of carbamazepine, phenytoin and allopurinol is most associated with the risks in the oriental population.

Original language	English
Pages (from-to)	188-190
Number of pages	3
Journal	Internal Medicine Journal
Volume	35
Issue number	3
DOIs	https://doi.org/10.1111/j.1445-5994.2005.00790.x
Publication status	Published - Mar 2005

Keywords

Adverse drug reaction
Case-control study
Relative risk
Stevens-Johnson syndrome
Toxic epidermal necrolysis

ASJC Scopus subject areas

Internal Medicine

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10.1111/j.1445-5994.2005.00790.x

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Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: A case-control study

Abstract

Keywords

ASJC Scopus subject areas

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