Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer

Yang Hong Dai; Yu Jen Chen; Chun Shu Lin; Kuen Tze Lin; Wen Yen Huang; Chang Ming Chen; Yu Fu Su; Chao Yueh Fan; Chen Hsiang Lo; Yen Fu Yang; Chih Cheng Tsao; Ming Yueh Liu; Po Chien Shen; Hsing Lung Chao; Kun San Chao

doi:10.21037/tro.2019.01.03

Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer

Yang Hong Dai, Yu Jen Chen, Chun Shu Lin, Kuen Tze Lin, Wen Yen Huang, Chang Ming Chen, Yu Fu Su, Chao Yueh Fan, Chen Hsiang Lo, Yen Fu Yang, Chih Cheng Tsao, Ming Yueh Liu, Po Chien Shen, Hsing Lung Chao, Kun San Chao

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Abstract

In early stage breast cancer, intraoperative radiation therapy (IORT) is a form of accelerated partial breast irradiation (APBI) that provides attractive therapeutic effects while shortening the overall treatment time and sparing the normal tissue radiation exposure. This technique has been used in Taiwan for several years in selected patients with breast cancer. However, some randomized trials pointed out that IORT is associated with higher rate of recurrence, therefore impeding its wider use as one of the standard managements in breast cancer. Also, despite its theoretical benefits for smaller tumor after surgery, the problem of recurrence warrants the necessity of strict and careful patient selection. The purpose of this article is to comprehensively review the updated consensus and current opinions on the use of IORT for early stage breast cancer.

Original language	English
Article number	4976
Journal	Therapeutic Radiology and Oncology
Volume	3
DOIs	https://doi.org/10.21037/tro.2019.01.03
Publication status	Published - Apr 2019
Externally published	Yes

Keywords

accelerated partial breast irradiation (APBI)
breast cancer
Intraoperative radiation therapy (IORT)

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Oncology
Radiology Nuclear Medicine and imaging
Oncology(nursing)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.21037/tro.2019.01.03

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Dai, Y. H., Chen, Y. J., Lin, C. S., Lin, K. T., Huang, W. Y., Chen, C. M., Su, Y. F., Fan, C. Y., Lo, C. H., Yang, Y. F., Tsao, C. C., Liu, M. Y., Shen, P. C., Chao, H. L., & Chao, K. S. (2019). Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer. Therapeutic Radiology and Oncology, 3, Article 4976. https://doi.org/10.21037/tro.2019.01.03

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title = "Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer",

abstract = "In early stage breast cancer, intraoperative radiation therapy (IORT) is a form of accelerated partial breast irradiation (APBI) that provides attractive therapeutic effects while shortening the overall treatment time and sparing the normal tissue radiation exposure. This technique has been used in Taiwan for several years in selected patients with breast cancer. However, some randomized trials pointed out that IORT is associated with higher rate of recurrence, therefore impeding its wider use as one of the standard managements in breast cancer. Also, despite its theoretical benefits for smaller tumor after surgery, the problem of recurrence warrants the necessity of strict and careful patient selection. The purpose of this article is to comprehensively review the updated consensus and current opinions on the use of IORT for early stage breast cancer.",

keywords = "accelerated partial breast irradiation (APBI), breast cancer, Intraoperative radiation therapy (IORT)",

author = "Dai, {Yang Hong} and Chen, {Yu Jen} and Lin, {Chun Shu} and Lin, {Kuen Tze} and Huang, {Wen Yen} and Chen, {Chang Ming} and Su, {Yu Fu} and Fan, {Chao Yueh} and Lo, {Chen Hsiang} and Yang, {Yen Fu} and Tsao, {Chih Cheng} and Liu, {Ming Yueh} and Shen, {Po Chien} and Chao, {Hsing Lung} and Chao, {Kun San}",

year = "2019",

month = apr,

doi = "10.21037/tro.2019.01.03",

language = "English",

volume = "3",

journal = "Therapeutic Radiology and Oncology",

issn = "2616-2768",

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T1 - Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer

AU - Dai, Yang Hong

AU - Chen, Yu Jen

AU - Lin, Chun Shu

AU - Lin, Kuen Tze

AU - Huang, Wen Yen

AU - Chen, Chang Ming

AU - Su, Yu Fu

AU - Fan, Chao Yueh

AU - Lo, Chen Hsiang

AU - Yang, Yen Fu

AU - Tsao, Chih Cheng

AU - Liu, Ming Yueh

AU - Shen, Po Chien

AU - Chao, Hsing Lung

AU - Chao, Kun San

PY - 2019/4

Y1 - 2019/4

N2 - In early stage breast cancer, intraoperative radiation therapy (IORT) is a form of accelerated partial breast irradiation (APBI) that provides attractive therapeutic effects while shortening the overall treatment time and sparing the normal tissue radiation exposure. This technique has been used in Taiwan for several years in selected patients with breast cancer. However, some randomized trials pointed out that IORT is associated with higher rate of recurrence, therefore impeding its wider use as one of the standard managements in breast cancer. Also, despite its theoretical benefits for smaller tumor after surgery, the problem of recurrence warrants the necessity of strict and careful patient selection. The purpose of this article is to comprehensively review the updated consensus and current opinions on the use of IORT for early stage breast cancer.

AB - In early stage breast cancer, intraoperative radiation therapy (IORT) is a form of accelerated partial breast irradiation (APBI) that provides attractive therapeutic effects while shortening the overall treatment time and sparing the normal tissue radiation exposure. This technique has been used in Taiwan for several years in selected patients with breast cancer. However, some randomized trials pointed out that IORT is associated with higher rate of recurrence, therefore impeding its wider use as one of the standard managements in breast cancer. Also, despite its theoretical benefits for smaller tumor after surgery, the problem of recurrence warrants the necessity of strict and careful patient selection. The purpose of this article is to comprehensively review the updated consensus and current opinions on the use of IORT for early stage breast cancer.

KW - accelerated partial breast irradiation (APBI)

KW - breast cancer

KW - Intraoperative radiation therapy (IORT)

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DO - 10.21037/tro.2019.01.03

M3 - Review article

AN - SCOPUS:85148867885

SN - 2616-2768

VL - 3

JO - Therapeutic Radiology and Oncology

JF - Therapeutic Radiology and Oncology

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ER -

Review of current perspectives on low-energy X-ray intraoperative radiotherapy in early stage breast cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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