TY - JOUR
T1 - Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in humans
AU - Yang, Cheryl C H
AU - Lai, Chi Wan
AU - Lai, Hsien Yong
AU - Kuo, Terry B J
N1 - Funding Information:
This study was supported by National Science Council (Taiwan) Grant NSC-89-2745-P-320-001 and NSC-89-2314-B-320-018.
PY - 2002/8/30
Y1 - 2002/8/30
N2 - To explore whether depth of sleep is related to changes in autonomic control, continuous power-spectral analysis of the electroencephalogram (EEG) and heart rate variability (HRV) was performed in ten normal subjects during nocturnal sleep. Quiet sleep (QS) was associated with an increase in high-frequency power (HF) of HRV (0.15-0.4 Hz) but a decrease in low-frequency power (LF) (0.04-0.15 Hz) to HF ratio (LF/HF) compared with awakening. During QS, LF/HF was significantly and negatively correlated with delta power of EEG (0.5-4.0 Hz), whereas mean R-R interval and HF were not. We conclude that during QS, cardiac sympathetic regulation is negatively related to the depth of sleep, although vagal regulation is not. Our methodology offers a quantitative analysis to study the interaction between cerebral cortical and autonomic functions.
AB - To explore whether depth of sleep is related to changes in autonomic control, continuous power-spectral analysis of the electroencephalogram (EEG) and heart rate variability (HRV) was performed in ten normal subjects during nocturnal sleep. Quiet sleep (QS) was associated with an increase in high-frequency power (HF) of HRV (0.15-0.4 Hz) but a decrease in low-frequency power (LF) (0.04-0.15 Hz) to HF ratio (LF/HF) compared with awakening. During QS, LF/HF was significantly and negatively correlated with delta power of EEG (0.5-4.0 Hz), whereas mean R-R interval and HF were not. We conclude that during QS, cardiac sympathetic regulation is negatively related to the depth of sleep, although vagal regulation is not. Our methodology offers a quantitative analysis to study the interaction between cerebral cortical and autonomic functions.
KW - Autonomic nervous system
KW - Electroencephalogram
KW - Heart rate variability
KW - Parasympathetic activity
KW - Power-spectral analysis
KW - Sleep
KW - Slow wave
KW - Sympathetic activity
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U2 - 10.1016/S0304-3940(02)00661-4
DO - 10.1016/S0304-3940(02)00661-4
M3 - Article
C2 - 12165415
AN - SCOPUS:0037199671
SN - 0304-3940
VL - 329
SP - 213
EP - 216
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 2
ER -