TY - JOUR
T1 - Regression of left ventricular mass after mitral valve repair of pure mitral regurgitation
AU - Shyu, Kou Gi
AU - Chen, Jin Jer
AU - Lin, Fang Yue
AU - Tsai, Chang Her
AU - Lin, Jiunn Lee
AU - Tseng, Yung Zu
AU - Lien, Wen Pin
PY - 1994/1/1
Y1 - 1994/1/1
N2 - To evaluate the effect of mitral valve repair on the regression of left ventricular mass, we studied 50 consecutive patients with severe, pure mitral regurgitation undergoing mitral valve repair. Two-dimensional echocardiograms were recorded a mean 2.5 ± 2.0 weeks before and 6.5 ± 2.5 months after valve operation. Postoperative significant mitral regurgitation was present in 3 patients. After mitral valve repair there were significant decreases in left ventricular end-diastolic volume index (133 ± 39 mL/m2 to 79 ± 35 mL/m2; p < 0.001), end-systolic volume index (44 ± 26 mL/m2 to 30 ± 26 mL/m2; p < 0.001), stroke volume index (89 ± 29 mL/m2 to 49 ± 19 mL/m2; p < 0.001), and mass index (211 ± 82 g/m2 to 134 ± 52 g/m2; p < 0.001). There also were significant decreases in left atrial dimension (47 ± 9 mm to 38 ± 9 mm; p < 0.001), left ventricular end-diastolic dimension (61 ± 8 mm to 48 ± 7 mm; p < 0.001), and end-systolic dimension (39 ± 8 mm to 32 ± 7 mm; p < 0.001). Left ventricular ejection fraction decreased slightly from 0.69 ± 0.12 to 0.64 ± 0.12; p < 0.01) after repair. Thus, correction of pure mitral regurgitation leads to reduction of the cardiac chamber size and left ventricular volumes as well as regression of the left ventricular mass.
AB - To evaluate the effect of mitral valve repair on the regression of left ventricular mass, we studied 50 consecutive patients with severe, pure mitral regurgitation undergoing mitral valve repair. Two-dimensional echocardiograms were recorded a mean 2.5 ± 2.0 weeks before and 6.5 ± 2.5 months after valve operation. Postoperative significant mitral regurgitation was present in 3 patients. After mitral valve repair there were significant decreases in left ventricular end-diastolic volume index (133 ± 39 mL/m2 to 79 ± 35 mL/m2; p < 0.001), end-systolic volume index (44 ± 26 mL/m2 to 30 ± 26 mL/m2; p < 0.001), stroke volume index (89 ± 29 mL/m2 to 49 ± 19 mL/m2; p < 0.001), and mass index (211 ± 82 g/m2 to 134 ± 52 g/m2; p < 0.001). There also were significant decreases in left atrial dimension (47 ± 9 mm to 38 ± 9 mm; p < 0.001), left ventricular end-diastolic dimension (61 ± 8 mm to 48 ± 7 mm; p < 0.001), and end-systolic dimension (39 ± 8 mm to 32 ± 7 mm; p < 0.001). Left ventricular ejection fraction decreased slightly from 0.69 ± 0.12 to 0.64 ± 0.12; p < 0.01) after repair. Thus, correction of pure mitral regurgitation leads to reduction of the cardiac chamber size and left ventricular volumes as well as regression of the left ventricular mass.
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U2 - 10.1016/0003-4975(94)91656-X
DO - 10.1016/0003-4975(94)91656-X
M3 - Article
C2 - 7979733
AN - SCOPUS:0028081238
SN - 0003-4975
VL - 58
SP - 1670
EP - 1673
JO - The Annals of Thoracic Surgery
JF - The Annals of Thoracic Surgery
IS - 6
ER -