Referral, Diagnosis, and Pharmacological Management of Peripheral Artery Disease: Perspectives from Taiwan

Jen Kuang Lee, I. Chang Hsieh, Chun Hung Su, Hsuan Li Huang, Meng Huan Lei, Kuan Ming Chiu, Chien Lung Huang, Chun Chi Chen, Po Chao Hsu, Chung Ho Hsu, Chun Yao Huang, Cheng Han Lee, Wei Chun Chang, Hsin Fu Lee, Ju Chi Liu, Hung I. Yeh

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)


Peripheral artery disease (PAD) imposes a heavy burden of major adverse cardiovascular events that are associated with considerable mortality and morbidity, and major adverse limb events (e.g., thrombectomy, revascularization, amputation) that can substantially impact patients’ daily functioning and quality of life. Global registry data have indicated that PAD is an underdiagnosed disease in Taiwan, and its associated risk factors remain inadequately controlled. This review discusses the burden of PAD in Taiwan, major guidelines on PAD management, and the latest clinical trial outcomes. Practical experience, opinions, and the latest trial data were integrated to derive a series of clinical algorithms – patient referral, PAD diagnosis, and the antithrombotic management of PAD. These algorithms can be adapted not only by physicians in Taiwan involved in the clinical management of patients with PAD but also by general practitioners in local clinics and regional hospital settings, with the ultimate aim of improving the totality of PAD patient care in Taiwan.

Original languageEnglish
Pages (from-to)97-108
Number of pages12
JournalActa Cardiologica Sinica
Issue number1
Publication statusPublished - Jan 2023


  • Antiplatelet therapy
  • Peripheral artery disease
  • Pharmacotherapy
  • Practice guidelines
  • Taiwan

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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