Recombinant factor VIIa use in refractory ulcer bleeding in uremic patient

An Yi Wang, Ang Yuan, Chien Hua Huang, Wei Tien Chang, Po Chin Liang, Tzu Hsin Lin, Shyr Chyr Chen

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Peptic ulcer bleeding is thought to be a major cause of bleeding in patients with end-stage renal disease and is more complicated in uremic patients. We described a 41-year-old man with end-stage renal disease who underwent hemodialysis with refractory ulcer bleeding, failure to all traditional peptic ulcer treatments, and correction of uremic component, who has been successfully treated by using recombinant factor VIIa. There have been few case reports in dealing refractory upper gastrointestinal bleeding in uremic patients in the literature; and in this case report, we demonstrates that recombinant factor VIIa could be used as a rescue therapy in these highsurgical risk patients when medical therapy fails.

Original languageEnglish
Pages (from-to)1319.e1-1319.e4
JournalAmerican Journal of Emergency Medicine
Issue number7
Publication statusPublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Emergency Medicine


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