Radiofrequency catheter ablation for treatment of Wolff-Parkinson-White syndrome - short- and long-term follow-up

Shih Ann Chen, Wing Ping Tsang, Chih Ping Hsia, Der Chih Wang, Chern En Chiang, Hon I. Yeh, Jaw Wen Chen, Chih Tai Ting, Chuen Wang Chiou, Chih Woon Kong, Shih Pu Wang, Benjamin N. Chiang, Mau Song Chang

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


One hundred and twenty-five patients with accessory pathways mediated tachyarrhythmias underwent radiofrequency ablation. Right-sided accessory pathways were ablated from the atrial aspect of the tricuspid anulus (all from the femoral vein approach) and the left-sided accessory pathways were ablated from the atrial or ventricular aspect of the mitral anulus. Immediately after the procedures, 3 of 8 accessory pathways (38%) and 131 of 137 accessory pathways (95%) were ablated successfully with radiofrequency through a small-tip (2 mm) and a large-tip (4 mm) electrode catheter, respectively. Seven of the 11 accessory pathways that failed radiofrequency ablation had a later successful direct current ablation. During follow-up (3 to 22 months), serial electrophysiological study showed that 11 of the 114 patients (10%) with successful ablation had return of accessory pathway conduction (2 had recurrence of tachycardia, 2%). Complications included accidental AV block (1 patient), cardiac tamponade (1 patient) and possible aortic dissection (1 patient). Transient proarrhythmic effects (more atrial and ventricular premature beats) were seen during the first week and sustained ventricular tachyarrhythmias were not inducible. In a successful session, procedure and radiation exposure times (including the time for diagnostic procedures) were 3.8 ± 0.2 h and 45 ± 4 min, respectively. This study confirms that radiofrequency ablation with a large-tip electrode catheter is an effective and relatively safe nonsurgical method for treatment of Wolff-Parkinson-White syndrome, with a low complication and recurrence rate.

Original languageEnglish
Pages (from-to)199-207
Number of pages9
JournalInternational Journal of Cardiology
Issue number2
Publication statusPublished - Nov 1992
Externally publishedYes


  • Accessory atrioventricular pathway
  • Catheter ablation
  • Radiofrequency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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