Quercetin simultaneously induces G₀/G₁-phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells

Medicine & Life Sciences

• Cell Cycle Resting Phase 89%
• HL-60 Cells 86%
• Quercetin 86%
• G1 Phase 77%
• Caspases 74%
• Autophagy 71%
• Leukemia 60%
• Apoptosis 45%
• Cell Death 15%
• Acute Myeloid Leukemia 12%
• Cyclin-Dependent Kinase Inhibitor p16 9%
• Autophagic Cell Death 9%
• Cyclin-Dependent Kinase Inhibitor p21 9%
• Cyclin-Dependent Kinase 2 9%
• Cyclin-Dependent Kinase 4 9%
• 3-methyladenine 9%
• Poly (ADP-Ribose) Polymerase-1 9%
• Caspase Inhibitors 8%
• DNA Fragmentation 7%
• Myeloid Cells 6%
• Flavonoids 6%
• Organelles 6%
• Light 4%
• Cell Proliferation 4%
• Cell Line 3%
• In Vitro Techniques 2%
• Neoplasms 2%

Earth & Environmental Sciences

• apoptosis 100%
• leukemia 97%
• cell 45%
• inhibitor 23%
• tumor 8%
• cleavage 8%
• fragmentation 7%
• assay 7%
• DNA 6%
• effect 1%

Chemical Compounds

• Quercetin 79%
• Cell Death 45%
• Apoptotic 24%
• Autophagy Inhibitor 20%
• 3-Methyladenine 18%
• P62 17%
• Cyclin Dependent Kinase Inhibitor 17%
• Cytoprotective 14%
• Poly(ADPribose) 14%
• Fragmentation 8%
• Cleavage 7%