Pyogenic liver abscess in end-stage renal disease patients: A nationwide longitudinal study

Lung Wen Tsai, Pei Wen Chao, Shuo Ming Ou, Yung Tai Chen, Chia Jen Shih, Szu Yuan Li, Tzen-Wen Chen, Tzeng Ji Chen, Chien Tsai Liu

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


End-stage renal disease (ESRD) patients are more prone to infectious disease because of their immunocompromised status. However, the association between pyogenic liver abscess (PLA) and ESRD remains not clear. The aim of our study is to evaluate the incidence, risk factors, and outcomes of PLA in ESRD patients. We recruited all incident ESRD patients from the Taiwan National Health Insurance database from 1998 to 2006. The incidence rate of PLA in ESRD patients was compared with that of a randomly selected non-ESRD control group matched for age, sex gender, Charlson comorbidity score, diabetes mellitus, and cirrhosis. Among the 57,761 incident dialysis patients, there were 538 cases of PLA. The incidence rate of PLA was 18.20 per 10,000 person-years in the ESRD cohort and 6.34 per 10,000 person-years in matched control cohort. The rate of PLA was significantly higher in the ESRD cohort (hazard ratio 3.63, 95% confidence interval 2.83-4.65, P

Original languageEnglish
Pages (from-to)72-79
Number of pages8
JournalHemodialysis International
Issue number1
Publication statusPublished - Jan 1 2015


  • End-stage renal disease
  • Liver disease
  • Pyogenic liver abscess
  • Renal replacement therapy
  • Taiwan

ASJC Scopus subject areas

  • Nephrology
  • Hematology


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