TY - JOUR
T1 - Pupillometry as an integrated readout of distinct attentional networks
AU - Strauch, Christoph
AU - Wang, Chin An
AU - Einhäuser, Wolfgang
AU - Van der Stigchel, Stefan
AU - Naber, Marnix
N1 - Funding Information:
S.V.d.S. was funded by a European Research Council consolidator grant ( ERC-CoG-863732) , M.N. was funded by an UitZicht grant ( 2018-10 , Rotterdamse Stichting Blindenbelangen), and C.-A.W. was funded by the Taiwan Ministry of Science and Technology ( 111-2628-H-008-003 ).
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/8
Y1 - 2022/8
N2 - The course of pupillary constriction and dilation provides an easy-to-access, inexpensive, and noninvasive readout of brain activity. We propose a new taxonomy of factors affecting the pupil and link these to associated neural underpinnings in an ascending hierarchy. In addition to two well-established low-level factors (light level and focal distance), we suggest two further intermediate-level factors, alerting and orienting, and a higher-level factor, executive functioning. Alerting, orienting, and executive functioning – including their respective underlying neural circuitries – overlap with the three principal attentional networks, making pupil size an integrated readout of distinct states of attention. As a now widespread technique, pupillometry is ready to provide meaningful applications and constitutes a viable part of the psychophysiological toolbox.
AB - The course of pupillary constriction and dilation provides an easy-to-access, inexpensive, and noninvasive readout of brain activity. We propose a new taxonomy of factors affecting the pupil and link these to associated neural underpinnings in an ascending hierarchy. In addition to two well-established low-level factors (light level and focal distance), we suggest two further intermediate-level factors, alerting and orienting, and a higher-level factor, executive functioning. Alerting, orienting, and executive functioning – including their respective underlying neural circuitries – overlap with the three principal attentional networks, making pupil size an integrated readout of distinct states of attention. As a now widespread technique, pupillometry is ready to provide meaningful applications and constitutes a viable part of the psychophysiological toolbox.
KW - alerting
KW - executive function
KW - locus coeruleus
KW - orienting
KW - superior colliculus
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U2 - 10.1016/j.tins.2022.05.003
DO - 10.1016/j.tins.2022.05.003
M3 - Review article
C2 - 35662511
AN - SCOPUS:85131442773
SN - 0166-2236
VL - 45
SP - 635
EP - 647
JO - Trends in Neurosciences
JF - Trends in Neurosciences
IS - 8
ER -