TY - JOUR
T1 - Psychological outcomes and medical morbidity of patients with bipolar disorder and Co-occurring alcohol use disorder
AU - Tang, Han Ching
AU - Chen, Pao Huan
AU - Chung, Kuo Hsuan
AU - Kuo, Chian Jue
AU - Huang, Shou-Hung
AU - Tsai, Shang Ying
N1 - Publisher Copyright:
© 2015 Taylor & Francis Group, LLC.
PY - 2015/10/2
Y1 - 2015/10/2
N2 - Objective: Patients with bipolar disorder are at a high risk for comorbid alcohol use disorder, and both disorders are associated with poor outcomes and multiple morbidities. This study aimed to explore not only the psychosocial functioning and psychopathological outcomes but also the medical morbidity of patients with bipolar disorder with and without alcohol use disorder. Methods: Outpatients with bipolar I disorder (DSM-IV) were recruited from a psychiatric teaching hospital in Taiwan (N = 393). Data on psychiatric symptoms, psychosocial functioning, and physical health were obtained through interviews with patients and collaterals, patient self-report, and medical record reviews. Results: Participants had a mean age of 41.1 years (SD = 11.9) and were mostly female (n = 255, 64.9%). Fewer than 10% (n = 34, 8.7%) met criteria for alcohol use disorder, and these participants were more likely to be male, to smoke, and to have a history of rapid cycling, higher mean body mass index, and higher incidences of gastrointestinal and hepatobiliary morbidities. A multiple logistic regression analysis revealed that patients with, versus those without, alcohol use disorder were more prone to gastrointestinal diseases (adjusted OR = 4.25, 95% CI [1.44-12.53], p
AB - Objective: Patients with bipolar disorder are at a high risk for comorbid alcohol use disorder, and both disorders are associated with poor outcomes and multiple morbidities. This study aimed to explore not only the psychosocial functioning and psychopathological outcomes but also the medical morbidity of patients with bipolar disorder with and without alcohol use disorder. Methods: Outpatients with bipolar I disorder (DSM-IV) were recruited from a psychiatric teaching hospital in Taiwan (N = 393). Data on psychiatric symptoms, psychosocial functioning, and physical health were obtained through interviews with patients and collaterals, patient self-report, and medical record reviews. Results: Participants had a mean age of 41.1 years (SD = 11.9) and were mostly female (n = 255, 64.9%). Fewer than 10% (n = 34, 8.7%) met criteria for alcohol use disorder, and these participants were more likely to be male, to smoke, and to have a history of rapid cycling, higher mean body mass index, and higher incidences of gastrointestinal and hepatobiliary morbidities. A multiple logistic regression analysis revealed that patients with, versus those without, alcohol use disorder were more prone to gastrointestinal diseases (adjusted OR = 4.25, 95% CI [1.44-12.53], p
KW - alcohol use disorders
KW - bipolar disorder
KW - comorbidity
KW - gastrointestinal diseases
KW - outcome
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U2 - 10.1080/15504263.2015.1113099
DO - 10.1080/15504263.2015.1113099
M3 - Article
C2 - 26683251
AN - SCOPUS:84951109791
SN - 1550-4263
VL - 11
SP - 184
EP - 188
JO - Journal of Dual Diagnosis
JF - Journal of Dual Diagnosis
IS - 3-4
ER -