Pseudomelanosis duodeni: report of eight cases.

K. Wang, H. J. Lin, C. L. Perng, H. Chiang, C. T. Lee, F. Y. Chang, S. D. Lee

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7 Citations (Scopus)


Pseudomelanosis duodeni is an uncommon endoscopic sign characterized by diffuse small black spots on the first and second portions of the duodenum. It occurs predominantly in female and elderly patients and is linked to chronic illnesses and related medications. Between 1988 and 1994, the authors saw eight patients with pseudomelanosis duodeni. To evaluate the nature of the pigments, special staining was performed in seven cases. Iron stain was strongly positive in three cases. Electron microscopy was performed in two cases. This revealed amorphous bodies within macrophage lysosomes in one case and angular crystals in another case. These tests suggest that in pseudomelanosis duodeni iron metabolism may be impaired and iron is pooled within macrophages.

Original languageEnglish
Pages (from-to)632-634
Number of pages3
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Issue number10
Publication statusPublished - Oct 1995
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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