Proximal deletion of the long arm of chromosome 1: [del(1)(q23-q25)]

L. J. Lo, M. S. Noordhoff, C. S. Huang, K. T. Chen, Y. R. Chen

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A patient with bilateral complete cleft of the lip and palate (CLP) had a proximal deletion of the long arm of chromosome 1 (1q). This rare chromosomal abnormality was characterized by pre- and postnatal growth retardation, psychomotor retardation, and specific craniofacial and other systemic anomalies. There is a high incidence of CLP in proximal 1q deletion syndrome, especially bilateral CLP. Twelve other cases reported in the literature having this deletion and associated anomalies were reviewed.

Original languageEnglish
Pages (from-to)586-589
Number of pages4
JournalCleft Palate-Craniofacial Journal
Issue number6
Publication statusPublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology


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