Primary appendiceal malignancy: A clinicopathologic study

Hwa Tzong Chen, Yeu Tsu M. Lee, Andy Shaw Bin Chou, Yung Kang Wu, Wun Yaw Yin, Ming Che Lee, Yung Hsiang Hsu

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Primary appendiceal cancer is a rare neoplasm. We analyzed the clinicopathologic characteristics and clinical outcomes of patients with primary appendiceal cancer treated at Buddhist Tzu Chi General Hospital in Eastern Taiwan. We reviewed the medical records of patients who had appendectomy at our hospital over a 10-year period and studied those who had histologically proven malignant appendiceal neoplasms. We treated eight such patients: seven males and one female. Their median age was 66 years (range, 59-78 years). There were three mucinous adenocarcinomas, two colonic type adenocarcinomas, and three adenocarcinoids. No patient was diagnosed correctly before surgery, and five (62.5%) had a preoperative diagnosis of acute appendicitis. Operative procedures included right hemicolectomy or partial colectomy in four, debulking and right hemicolectomy in three, and appendectomy only in one. With a mean follow-up of 64 months (range, 3-132), patients with adenocarcinoid lesions had better prognosis than those with adenocarcinomas. The important prognostic factors of primary appendiceal cancer included histologic subtypes and the extent of dissemination. In our series, palliative resection for disseminated lesions with or without additional chemotherapy resulted in long-term survival.

Original languageEnglish
Pages (from-to)618-625
Number of pages8
JournalKaohsiung Journal of Medical Sciences
Volume22
Issue number12
DOIs
Publication statusPublished - Dec 2006
Externally publishedYes

Keywords

  • Adenocarcinoid
  • Appendiceal cancer
  • Colonic type adenocarcinoma
  • Mucinous cystadenocarcinoma
  • Pseudomyxoma peritonei

ASJC Scopus subject areas

  • General Medicine

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