Abstract
Adrenal insufficiency, though rare, is a well-known complication of acquired immunodeficiency syndrome (AIDS). Over the past 9 years at the National Taiwan University Hospital, 4 patients were diagnosed with primary adrenal insufficiency among 854 non-hemophiliac patients with human immunodeficiency virus infection, with an incidence of 0.19 per 100 patient-years (95% confidence interval, 0.17-0.21 per 100 patient-years). All of the 4 patients were severely immunosuppressed and had been diagnosed with at least 1 AIDS-defining opportunistic illness ever reported to produce adrenal insufficiency in AIDS patients. In 1 of the patients, fluconazole was considered contributory to the development of adrenal insufficiency after treatment at a daily dose of 800 mg for 68 days.
Original language | English |
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Pages (from-to) | 250-253 |
Number of pages | 4 |
Journal | Journal of Microbiology, Immunology and Infection |
Volume | 37 |
Issue number | 4 |
Publication status | Published - Aug 2004 |
Externally published | Yes |
Keywords
- Acquired immunodeficiency syndrome
- Adrenal gland diseases
- Opportunistic infections
- Pneumocystis pneumonia
ASJC Scopus subject areas
- Immunology and Allergy
- General Immunology and Microbiology
- Microbiology (medical)
- Infectious Diseases