Premature rupture of the membranes: a cause for neonatal osteomyelitis?

Sui-Ling Liao, Shen Hao Lai, Tzou-Yien Lin, Yi-Hong Chou, Jen-Fu Hsu

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Osteomyelitis is rare in the neonatal period. Many etiologic factors for causing neonatal osteomyelitis have been discussed in the literature; however, premature rupture of the membranes has never been emphasized. We report on a neonate with osteomyelitis of the right humerus infected with an uncommon pathogen, Klebsiella pneumonia. In the absence of any perinatal disease, premature rupture of the membranes was suggested to be the cause of the illness. The infant was initially regarded as having Erb palsy because of the absence of systemic symptoms and lack of perinatal high-risk factors. Antibiotic administration was delayed for 3 weeks. Luckily, nearly complete recovery was noted after 2 months of follow up. We emphasize the importance of considering osteomyelitis in a newborn infant with limb palsy, particularly in the presence of premature rupture of the membranes of the mother. We also discuss the results of the microbial examination and significance of magnetic resonance imaging in neonatal osteomyelitis.

Original languageEnglish
Pages (from-to)63-6
Number of pages4
JournalAmerican Journal of Perinatology
Issue number2
Publication statusPublished - Feb 2005
Externally publishedYes


  • Anti-Bacterial Agents
  • Brachial Plexus Neuropathies
  • Ceftazidime
  • Diagnosis, Differential
  • Female
  • Fetal Membranes, Premature Rupture
  • Humans
  • Infant, Newborn
  • Klebsiella Infections
  • Klebsiella pneumoniae
  • Osteomyelitis
  • Pregnancy
  • Shoulder
  • Synovitis
  • Treatment Outcome
  • Case Reports
  • Journal Article


Dive into the research topics of 'Premature rupture of the membranes: a cause for neonatal osteomyelitis?'. Together they form a unique fingerprint.

Cite this