Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved semen from a man with testicular cancer

Shee Uan Chen, Hong Nerng Ho, Hsin Fu Chen, Su Cheng Huang, Tzu Yao Lee, Yu Shih Yang

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

A successful pregnancy was achieved by intracytoplasmic sperm injection (ICSI) using cryopreserved semen from a man with testicular cancer. He was a victim of right testicular seminoma, and was azoospermic after right orchidectomy and radiotherapy. The wife had had three successive failures of intrauterine insemination (IUI) using semen that was cryopreserved before radiotherapy. The couple then underwent in-vitro fertilization (IVF) treatment. ICSI was performed because the sperm motility was extremely poor after thawing. Eight of 12 injected oocytes had normal fertilization and embryo cleavage. After replacement of four embryos, a singleton pregnancy developed. She delivered a healthy male baby at 39 weeks gestation. In addition to IUI and IVF, ICSI further provides male patients with cancer an improved chance of fathering a child. Any men diagnosed with cancer who have not yet finished their families should have their spermatozoa frozen before treatment, regardless of its quality.

Original languageEnglish
Pages (from-to)2645-2647
Number of pages3
JournalHuman Reproduction
Volume11
Issue number12
DOIs
Publication statusPublished - Jan 1 1996
Externally publishedYes

Keywords

  • Cryopreserved semen
  • Intracytoplasmic sperm injection
  • Testicular cancer

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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