Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors

Hung Chuen Chang; Yu Min Lin; Amy Ming Fang Yen; Sam Li Sheng Chen; Wendy Yi Ying Wu; Sherry Yueh Hsia Chiu; Jean Ching Yuan Fann; Yueh Shih Lin; Hsiu Hsi Chen; Chao Sheng Liao

Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors

Hung Chuen Chang, Yu Min Lin, Amy Ming Fang Yen, Sam Li Sheng Chen, Wendy Yi Ying Wu, Sherry Yueh Hsia Chiu, Jean Ching Yuan Fann, Yueh Shih Lin, Hsiu Hsi Chen, Chao Sheng Liao

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Aim: Locoregional treatment [including percutaneous ethanol injection (PEI) therapy and transcatheter arterial chemoembolization (TACE)] provides an alternative treatment for early-diagnosed hepatocellular carcinoma (HCC). However, the long-term survival of patients after locoregional treatments remains unclear. Patients and Methods: A total of 108 patients with small HCC not indicated for surgical hepatic resection were recruited between 1991 and 1999. All patients received first treatment with PEI therapy alone or combined with TACE. We followed-up these patients until the end of 2007. Clinical attributes and biological markers in association with long-term survival were collected. Significant predictors were identified by using proportional hazards regression model. Results: The overall 1-, 3-, 5-, and 10-year cumulative survival of patients with HCC (

Original language	English
Pages (from-to)	5171-5178
Number of pages	8
Journal	Anticancer Research
Volume	33
Issue number	11
Publication status	Published - Nov 2013

Keywords

Aspartate aminotransferase
Child-Pugh score
Hepatocellular carcinoma
Percutaneous ethanol injection
Survival
Transcatheter arterial chemoembolization

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@article{0d067213b1064050be688a3e9205db06,

title = "Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors",

abstract = "Aim: Locoregional treatment [including percutaneous ethanol injection (PEI) therapy and transcatheter arterial chemoembolization (TACE)] provides an alternative treatment for early-diagnosed hepatocellular carcinoma (HCC). However, the long-term survival of patients after locoregional treatments remains unclear. Patients and Methods: A total of 108 patients with small HCC not indicated for surgical hepatic resection were recruited between 1991 and 1999. All patients received first treatment with PEI therapy alone or combined with TACE. We followed-up these patients until the end of 2007. Clinical attributes and biological markers in association with long-term survival were collected. Significant predictors were identified by using proportional hazards regression model. Results: The overall 1-, 3-, 5-, and 10-year cumulative survival of patients with HCC (",

keywords = "Aspartate aminotransferase, Child-Pugh score, Hepatocellular carcinoma, Percutaneous ethanol injection, Survival, Transcatheter arterial chemoembolization",

author = "Chang, {Hung Chuen} and Lin, {Yu Min} and Yen, {Amy Ming Fang} and Chen, {Sam Li Sheng} and Wu, {Wendy Yi Ying} and Chiu, {Sherry Yueh Hsia} and Fann, {Jean Ching Yuan} and Lin, {Yueh Shih} and Chen, {Hsiu Hsi} and Liao, {Chao Sheng}",

year = "2013",

month = nov,

language = "English",

volume = "33",

pages = "5171--5178",

journal = "Anticancer Research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "11",

}

TY - JOUR

T1 - Predictors of long-term survival in hepatocellular carcinomas

T2 - A longitudinal follow-up of 108 patients with small tumors

AU - Chang, Hung Chuen

AU - Lin, Yu Min

AU - Yen, Amy Ming Fang

AU - Chen, Sam Li Sheng

AU - Wu, Wendy Yi Ying

AU - Chiu, Sherry Yueh Hsia

AU - Fann, Jean Ching Yuan

AU - Lin, Yueh Shih

AU - Chen, Hsiu Hsi

AU - Liao, Chao Sheng

PY - 2013/11

Y1 - 2013/11

N2 - Aim: Locoregional treatment [including percutaneous ethanol injection (PEI) therapy and transcatheter arterial chemoembolization (TACE)] provides an alternative treatment for early-diagnosed hepatocellular carcinoma (HCC). However, the long-term survival of patients after locoregional treatments remains unclear. Patients and Methods: A total of 108 patients with small HCC not indicated for surgical hepatic resection were recruited between 1991 and 1999. All patients received first treatment with PEI therapy alone or combined with TACE. We followed-up these patients until the end of 2007. Clinical attributes and biological markers in association with long-term survival were collected. Significant predictors were identified by using proportional hazards regression model. Results: The overall 1-, 3-, 5-, and 10-year cumulative survival of patients with HCC (

AB - Aim: Locoregional treatment [including percutaneous ethanol injection (PEI) therapy and transcatheter arterial chemoembolization (TACE)] provides an alternative treatment for early-diagnosed hepatocellular carcinoma (HCC). However, the long-term survival of patients after locoregional treatments remains unclear. Patients and Methods: A total of 108 patients with small HCC not indicated for surgical hepatic resection were recruited between 1991 and 1999. All patients received first treatment with PEI therapy alone or combined with TACE. We followed-up these patients until the end of 2007. Clinical attributes and biological markers in association with long-term survival were collected. Significant predictors were identified by using proportional hazards regression model. Results: The overall 1-, 3-, 5-, and 10-year cumulative survival of patients with HCC (

KW - Aspartate aminotransferase

KW - Child-Pugh score

KW - Hepatocellular carcinoma

KW - Percutaneous ethanol injection

KW - Survival

KW - Transcatheter arterial chemoembolization

UR - http://www.scopus.com/inward/record.url?scp=84891363524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891363524&partnerID=8YFLogxK

M3 - Article

C2 - 24222166

AN - SCOPUS:84891363524

SN - 0250-7005

VL - 33

SP - 5171

EP - 5178

JO - Anticancer Research

JF - Anticancer Research

IS - 11

ER -

Predictors of long-term survival in hepatocellular carcinomas: A longitudinal follow-up of 108 patients with small tumors

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Other files and links

Fingerprint

Cite this