Abstract
The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio is a promising risk predictor of metabolic syndrome (MetS) and to determine the optimal cut-off value of this ratio in detecting subjects with MetS in a Chinese population. A prospective study was conducted using a representative sample of non-institutionized people in Taiwan. A total of 3,343 participants with mean age (±SD) of 39.86 (±15.61) years old were followed up from 2002 to 2007. The primary outcome was the incidence of MetS. The MetS was defined according to a unified criterion established by several major organizations. There were 462 cases of incident MetS during a mean follow-up period of 5.26 years. A significantly stepwise increase in the incidence of MetS across quartiles of the apoB/apoA-I ratio was noted in both sexes after adjustment for potential confounders (p for trend
Original language | English |
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Pages (from-to) | 404-414 |
Number of pages | 11 |
Journal | Endocrine |
Volume | 49 |
Issue number | 2 |
DOIs | |
Publication status | Published - Oct 12 2014 |
Keywords
- Apolipoprotein B/apolipoprotein A-I ratio
- Cohort study
- Metabolic syndrome
- Risk predictor
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism