Predictive value of serum apolipoprotein B/apolipoprotein A-I ratio in metabolic syndrome risk: a Chinese cohort study

Yu Ching Chou; Jen Chun Kuan; Chyi-Huey Bai; Tsan Yang; Wan Yun Chou; Po Chien Hsieh; San Lin You; Lee Ching Hwang; Chien Hua Chen; Cheng Yu Wei; Chien An Sun

doi:10.1007/s12020-014-0447-z

Predictive value of serum apolipoprotein B/apolipoprotein A-I ratio in metabolic syndrome risk: a Chinese cohort study

Yu Ching Chou, Jen Chun Kuan, Chyi-Huey Bai, Tsan Yang, Wan Yun Chou, Po Chien Hsieh, San Lin You, Lee Ching Hwang, Chien Hua Chen, Cheng Yu Wei, Chien An Sun

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio is a promising risk predictor of metabolic syndrome (MetS) and to determine the optimal cut-off value of this ratio in detecting subjects with MetS in a Chinese population. A prospective study was conducted using a representative sample of non-institutionized people in Taiwan. A total of 3,343 participants with mean age (±SD) of 39.86 (±15.61) years old were followed up from 2002 to 2007. The primary outcome was the incidence of MetS. The MetS was defined according to a unified criterion established by several major organizations. There were 462 cases of incident MetS during a mean follow-up period of 5.26 years. A significantly stepwise increase in the incidence of MetS across quartiles of the apoB/apoA-I ratio was noted in both sexes after adjustment for potential confounders (p for trend

Original language	English
Pages (from-to)	404-414
Number of pages	11
Journal	Endocrine
Volume	49
Issue number	2
DOIs	https://doi.org/10.1007/s12020-014-0447-z
Publication status	Published - Oct 12 2014

Keywords

Apolipoprotein B/apolipoprotein A-I ratio
Cohort study
Metabolic syndrome
Risk predictor

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s12020-014-0447-z

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title = "Predictive value of serum apolipoprotein B/apolipoprotein A-I ratio in metabolic syndrome risk: a Chinese cohort study",

abstract = "The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio is a promising risk predictor of metabolic syndrome (MetS) and to determine the optimal cut-off value of this ratio in detecting subjects with MetS in a Chinese population. A prospective study was conducted using a representative sample of non-institutionized people in Taiwan. A total of 3,343 participants with mean age (±SD) of 39.86 (±15.61) years old were followed up from 2002 to 2007. The primary outcome was the incidence of MetS. The MetS was defined according to a unified criterion established by several major organizations. There were 462 cases of incident MetS during a mean follow-up period of 5.26 years. A significantly stepwise increase in the incidence of MetS across quartiles of the apoB/apoA-I ratio was noted in both sexes after adjustment for potential confounders (p for trend ",

keywords = "Apolipoprotein B/apolipoprotein A-I ratio, Cohort study, Metabolic syndrome, Risk predictor",

author = "Chou, {Yu Ching} and Kuan, {Jen Chun} and Chyi-Huey Bai and Tsan Yang and Chou, {Wan Yun} and Hsieh, {Po Chien} and You, {San Lin} and Hwang, {Lee Ching} and Chen, {Chien Hua} and Wei, {Cheng Yu} and Sun, {Chien An}",

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doi = "10.1007/s12020-014-0447-z",

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T2 - a Chinese cohort study

AU - Chou, Yu Ching

AU - Kuan, Jen Chun

AU - Bai, Chyi-Huey

AU - Yang, Tsan

AU - Chou, Wan Yun

AU - Hsieh, Po Chien

AU - You, San Lin

AU - Hwang, Lee Ching

AU - Chen, Chien Hua

AU - Wei, Cheng Yu

AU - Sun, Chien An

PY - 2014/10/12

Y1 - 2014/10/12

N2 - The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio is a promising risk predictor of metabolic syndrome (MetS) and to determine the optimal cut-off value of this ratio in detecting subjects with MetS in a Chinese population. A prospective study was conducted using a representative sample of non-institutionized people in Taiwan. A total of 3,343 participants with mean age (±SD) of 39.86 (±15.61) years old were followed up from 2002 to 2007. The primary outcome was the incidence of MetS. The MetS was defined according to a unified criterion established by several major organizations. There were 462 cases of incident MetS during a mean follow-up period of 5.26 years. A significantly stepwise increase in the incidence of MetS across quartiles of the apoB/apoA-I ratio was noted in both sexes after adjustment for potential confounders (p for trend

AB - The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio is a promising risk predictor of metabolic syndrome (MetS) and to determine the optimal cut-off value of this ratio in detecting subjects with MetS in a Chinese population. A prospective study was conducted using a representative sample of non-institutionized people in Taiwan. A total of 3,343 participants with mean age (±SD) of 39.86 (±15.61) years old were followed up from 2002 to 2007. The primary outcome was the incidence of MetS. The MetS was defined according to a unified criterion established by several major organizations. There were 462 cases of incident MetS during a mean follow-up period of 5.26 years. A significantly stepwise increase in the incidence of MetS across quartiles of the apoB/apoA-I ratio was noted in both sexes after adjustment for potential confounders (p for trend

KW - Apolipoprotein B/apolipoprotein A-I ratio

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KW - Metabolic syndrome

KW - Risk predictor

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Predictive value of serum apolipoprotein B/apolipoprotein A-I ratio in metabolic syndrome risk: a Chinese cohort study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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