Objective: To identify meaningful changes in patients in 3 functional domains (basic mobility [BM], daily activity [DA], and applied cognition [AC]) after discharge from inpatient stroke rehabilitation and to identify the predictors of 1-year functional improvement. Design: A longitudinal, multicenter, prospective cohort study. Setting: The acute care wards of 3 hospitals in the Greater Taipei area of Taiwan. Participants: Five hundred patients with stroke in acute care wards (mean age=60±12.2 years, 62% men, N=500). Interventions: Not applicable. Main Outcome Measure(s): The Mandarin version of the Activity Measure for Post-Acute Care (AM-PAC) short forms were assessed at discharge and 3-, 6-, and 12-month follow-up. The minimal detectable change (MDC) was used to categorize changes in the scores as improved and unimproved at the 4 time points. Results: The mean scores of the AM-PAC BM and DA subscales substantially increased over the first 3 months after discharge (86% of participants exhibited improvement) and slightly increased during the subsequent 9 months (5∼26% of participants exhibited improvement). However, the mean score of the AC subscale decreased within the first 3 months and increased over the subsequent 9 months (22-23% of participants exhibited improvement). The BM, AC scores at discharge were the dominant predictors of subsequent functional improvement (P<.05). Patients with a higher functional stage at discharge were more likely to experience significant improvement. Conclusion: This study established the capacity of the AM-PAC to predict functional improvement in 3 domains during the early, middle, and late stages of recovery. The findings can assist clinicians in identifying patients at risk of unfavorable long-term functional recovery and providing such patients with tailored interventions during the early stage of rehabilitation.

Original languageEnglish
Pages (from-to)487-497
Number of pages11
JournalArchives of Physical Medicine and Rehabilitation
Issue number3
Publication statusAccepted/In press - 2023


  • Functional outcomes
  • Rehabilitation
  • Stroke
  • Subacute care

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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