Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor

Po Yuan Chen; Yu Chi Wu; Tzu Hurng Cheng; Tzu Ching Shih; Cing Tsan Tsai; Chieh Hsi Wu; Tzu Yu Hua; Yen Yu Huang; Chia Hsing Cheng; Ming Jen Fan

doi:10.1109/BIBE.2011.68

Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor

Po Yuan Chen, Yu Chi Wu, Tzu Hurng Cheng, Tzu Ching Shih, Cing Tsan Tsai, Chieh Hsi Wu, Tzu Yu Hua, Yen Yu Huang, Chia Hsing Cheng, Ming Jen Fan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.

Original language	English
Title of host publication	Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011
Pages	209-212
Number of pages	4
DOIs	https://doi.org/10.1109/BIBE.2011.68
Publication status	Published - 2011
Externally published	Yes
Event	2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011 - Taichung, Taiwan Duration: Oct 24 2011 → Oct 26 2011

Publication series

Name	Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011

Other

Other	2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011
Country/Territory	Taiwan
City	Taichung
Period	10/24/11 → 10/26/11

Keywords

Fas receptor
cell apoptosis
curcumin
docking
oral cancer

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/BIBE.2011.68

Cite this

Chen, P. Y., Wu, Y. C., Cheng, T. H., Shih, T. C., Tsai, C. T., Wu, C. H., Hua, T. Y., Huang, Y. Y., Cheng, C. H., & Fan, M. J. (2011). Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor. In Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011 (pp. 209-212). Article 6092531 (Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011). https://doi.org/10.1109/BIBE.2011.68

Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor. / Chen, Po Yuan; Wu, Yu Chi; Cheng, Tzu Hurng et al.
Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011. 2011. p. 209-212 6092531 (Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chen, PY, Wu, YC, Cheng, TH, Shih, TC, Tsai, CT, Wu, CH, Hua, TY, Huang, YY, Cheng, CH & Fan, MJ 2011, Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor. in Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011., 6092531, Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011, pp. 209-212, 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011, Taichung, Taiwan, 10/24/11. https://doi.org/10.1109/BIBE.2011.68

Chen PY, Wu YC, Cheng TH, Shih TC, Tsai CT, Wu CH et al. Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor. In Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011. 2011. p. 209-212. 6092531. (Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011). doi: 10.1109/BIBE.2011.68

Chen, Po Yuan ; Wu, Yu Chi ; Cheng, Tzu Hurng et al. / Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor. Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011. 2011. pp. 209-212 (Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011).

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title = "Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor",

abstract = "Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.",

keywords = "Fas receptor, cell apoptosis, curcumin, docking, oral cancer",

author = "Chen, {Po Yuan} and Wu, {Yu Chi} and Cheng, {Tzu Hurng} and Shih, {Tzu Ching} and Tsai, {Cing Tsan} and Wu, {Chieh Hsi} and Hua, {Tzu Yu} and Huang, {Yen Yu} and Cheng, {Chia Hsing} and Fan, {Ming Jen}",

note = "Funding Information: Work performed under the auspices of the U.S. Department of Energy and the University of Arizona.; 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011 ; Conference date: 24-10-2011 Through 26-10-2011",

year = "2011",

doi = "10.1109/BIBE.2011.68",

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AU - Wu, Yu Chi

AU - Cheng, Tzu Hurng

AU - Shih, Tzu Ching

AU - Tsai, Cing Tsan

AU - Wu, Chieh Hsi

AU - Hua, Tzu Yu

AU - Huang, Yen Yu

AU - Cheng, Chia Hsing

AU - Fan, Ming Jen

N1 - Funding Information: Work performed under the auspices of the U.S. Department of Energy and the University of Arizona.

PY - 2011

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N2 - Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.

AB - Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.

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Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor

Abstract

Publication series

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Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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