POWER: PhylOgenetic WEb Repeater - An integrated and user-optimized framework for biomolecular phylogenetic analysis

Chung Yen Lin, Fan Kai Lin, Chieh Hua Lin, Li Wei Lai, Hsiu Jun Hsu, Shu Hwa Chen, Chao A. Hsiung

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

POWER, the PhylOgenetic WEb Repeater, is a web-based service designed to perform user-friendly pipeline phylogenetic analysis. POWER uses an open-source LAMP structure and infers genetic distances and phylogenetic relationships using well-established algorithms (ClustalW and PHYLIP). POWER incorporates a novel tree builder based on the GD library to generate a high-quality tree topology according to the calculated result. POWER accepts either raw sequences in FASTA format or user-uploaded alignment output files. Through a user-friendly web interface, users can sketch a tree effortlessly in multiple steps. After a tree has been generated, users can freely set and modify parameters, select tree building algorithms, refine sequence alignments or edit the tree topology. All the information related to input sequences and the processing history is logged and downloadable for the user's reference. Furthermore, iterative tree construction can be performed by adding sequences to, or removing them from, a previously submitted job. POWER is accessible at http://power.nhri.org.tw.

Original languageEnglish
Pages (from-to)W553-W556
JournalNucleic Acids Research
Volume33
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Jul 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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