Polymyositis complicating donor lymphocyte infusion after stem cell transplantation for relapsed chronic myeloid leukemia: Report of a case and review of literature

Feng Cheng Liu; Chen Hung Chen; Tsu Yi Chao

doi:10.1007/s10067-006-0346-7

Polymyositis complicating donor lymphocyte infusion after stem cell transplantation for relapsed chronic myeloid leukemia: Report of a case and review of literature

Feng Cheng Liu, Chen Hung Chen, Tsu Yi Chao

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyositis. We report in this study a 25-year-old man who suffered from a relapse of CML 4 years after a sibling human leukocyte antigen-matched allogenic BMT. The patient developed polymyositis 18 months after DLI. Mini-pulse therapy with methylprednisolone was effective for his proximal weakness and elevated creatine phosphokinase. There was no relapse of symptoms of polymyositis on tapering of the medication.

Original language	English
Pages (from-to)	1207-1210
Number of pages	4
Journal	Clinical Rheumatology
Volume	26
Issue number	7
DOIs	https://doi.org/10.1007/s10067-006-0346-7
Publication status	Published - Jul 2007
Externally published	Yes

Keywords

Donor lymphocyte infusion
Graftvs host disease
Polymyositis

ASJC Scopus subject areas

Rheumatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10067-006-0346-7

Cite this

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title = "Polymyositis complicating donor lymphocyte infusion after stem cell transplantation for relapsed chronic myeloid leukemia: Report of a case and review of literature",

abstract = "Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyositis. We report in this study a 25-year-old man who suffered from a relapse of CML 4 years after a sibling human leukocyte antigen-matched allogenic BMT. The patient developed polymyositis 18 months after DLI. Mini-pulse therapy with methylprednisolone was effective for his proximal weakness and elevated creatine phosphokinase. There was no relapse of symptoms of polymyositis on tapering of the medication.",

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T2 - Report of a case and review of literature

AU - Liu, Feng Cheng

AU - Chen, Chen Hung

AU - Chao, Tsu Yi

PY - 2007/7

Y1 - 2007/7

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AB - Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyositis. We report in this study a 25-year-old man who suffered from a relapse of CML 4 years after a sibling human leukocyte antigen-matched allogenic BMT. The patient developed polymyositis 18 months after DLI. Mini-pulse therapy with methylprednisolone was effective for his proximal weakness and elevated creatine phosphokinase. There was no relapse of symptoms of polymyositis on tapering of the medication.

KW - Donor lymphocyte infusion

KW - Graftvs host disease

KW - Polymyositis

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Polymyositis complicating donor lymphocyte infusion after stem cell transplantation for relapsed chronic myeloid leukemia: Report of a case and review of literature

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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