Polyamine interaction with Z-DNA

K. Tomita, T. Hakoshima, K. Inubushi, S. Kunisawa, H. Ohishi, G. A. van der Marel, J. H. van Boom, A. H.J. Wang, A. Rich

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


In order to elucidate the detailed Z-DNA interaction with polyamines and also to clarify the mutual molecular recognition between the left-handed helix and the biologically important polyamine molecule, several polyamine-Z-DNA hexamer complexes were crystallized and their crystal structures were determined by X-ray diffraction. The general interaction modes found in these crystal structures were discussed in comparison with those in the complexes between polyamine and the right-handed DNA or RNA.

Original languageEnglish
Pages (from-to)71-75
Number of pages5
JournalJournal of Molecular Graphics
Issue number2
Publication statusPublished - Jun 1989
Externally publishedYes


  • polyamine-Z-DNA complexes
  • X-ray structure analysis

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry


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