Plasma-cell cheilitis: Successful treatment with intralesional injections of corticosteroids

Jonathan Te Peng Tseng, Chien-Jui Cheng, Woan-Ruoh Lee, Kuo-Hsien Wang

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Plasma-cell cheilitis is a rare inflammatory disorder of the lip characterized histologically by a band-like infiltrate of plasma cells in the upper dermis. It is considered an oral counterpart of plasma-cell balanitis. Clinically, it presents as a circumscribed, flat to slightly raised, eroded area of the lip. The cause of plasma-cell cheilitis is unknown, and the treatment is often disappointing. We describe a 55-year-old woman who had a long-lasting painful, swollen, and eroded area on her lips, which responded poorly to various topical treatments. Biopsy showed a band-like infiltrate composed mainly of mature plasma cells in the dermis. A diagnosis of plasma-cell cheilitis was made after excluding contact dermatitis, lichen planus, bacterial, fungal and spirochaete infections, and an extramedullary plasmacytoma. Dramatic improvements were observed after intralesional injections of corticosteroids. The lesion cleared up after two treatments, and there has been no recurrence in 1 year of follow-up.

Original languageEnglish
Pages (from-to)174-177
Number of pages4
JournalClinical and Experimental Dermatology
Issue number2
Publication statusPublished - Mar 2009

ASJC Scopus subject areas

  • Dermatology


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