Pituitary metastasis from bronchogenic adenocarcinoma

Chuang Wei Chen, Yung Hsiao Chiang, Cheng Yu Chen, Herng Sheng Lee, Yih Huei Su

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Tumor metastases to the pituitary gland are a rare complication of systemic cancer. We described a 64-year-old male with pituitary metastasis from bronchogenic adenocarcinoma. The patient had undergone the first course of chemotherapy and local radiotherapy for the lung cancer. However, he suffered from rapid onset of adrenal insufficiency accompanied by the sequentially progressive headache, blurred vision, polyuria, and polydipsia. The examination revealed the results of panhypopituitarism, bitemporal hemianopsia, and diabetes insipidus. Magnetic resonance image showed an intrasellar and suprasellar dumbbell-shaped mass. Metastatic bronchogenic adenocarcinoma was diagnosed by biopsy of the pituitary tumor. Metastatic tumors to the pituitary gland can mimic a nonfunctional pituitary adenoma or other sellar lesions in clinical presentation and imaging. The endoscopic transsphenoidal approach provides for minimal invasive surgery for tissue biopsy and decompression, and improves the quality of life in symptomatic patients.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalJournal of Medical Sciences
Issue number3
Publication statusPublished - Jun 2005
Externally publishedYes


  • Bronchogenic adenocarcinoma
  • Panhypopituitarism
  • Pituitary gland metastasis

ASJC Scopus subject areas

  • General Medicine


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