Phenolic antioxidants from the heartwood of Acacia confusa

Jyh Horng Wu, Yu Tang Tung, Sheng Yang Wang, Lie Fen Shyur, Yueh Hsiung Kuo, Shang Tzen Chang

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)


In the present study, the ethanolic extracts from the heartwood of Acacia confusa, a species indigenous to Taiwan, exhibit strong antioxidant effects. Among all the fractions from ethanolic extracts of heartwood, the EtOAc soluble fraction exhibits the best antioxidant activity. The 80% 1,1-diphenyl-2- picrylhydrazyl radical inhibitory activity by the EtOAc extract was observed at a concentration of 5 μg/mL, and at the same dosage there was a similar free radical scavenging activity for (-)-ascorbic acid and (+)-catechin, both of which are well-known antioxidants. In addition, the EtOAc extract also protects ΦX174 supercoiled DNA against strand scission induced by hydroxyl radical. Furthermore, following by column chromatography and reverse-phase high-performance liquid chromatorgrapy, 10 pure phenolic compounds, including three major antioxidants (3,7,8,3′,4′-pentahydroxyflavone, 7,8,3′,4′-tetrahydroxy-3-methoxyflavone, and 3,4,2′,3′, 4′-pentahydroxy-trans-chalcone) and a new flavonoid (3,7,8,3′- tetrahydroxy-4′-methoxyflavone), were isolated from the ethanolic extracts of A. confusa heartwood.

Original languageEnglish
Pages (from-to)5917-5921
Number of pages5
JournalJournal of Agricultural and Food Chemistry
Issue number15
Publication statusPublished - Jul 27 2005
Externally publishedYes


  • Acacia confusa
  • Antioxidant
  • Flavonoids
  • Free radical
  • Phenolic compounds

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Food Science
  • Chemistry (miscellaneous)


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