TY - JOUR
T1 - Phase-Dependent MoS2Nanoflowers for Light-Driven Antibacterial Application
AU - Mutalik, Chinmaya
AU - Krisnawati, Dyah Ika
AU - Patil, Shivaraj B.
AU - Khafid, Muhamad
AU - Atmojo, Didik Susetiyanto
AU - Santoso, Puguh
AU - Lu, Ssu Chiao
AU - Wang, Di Yan
AU - Kuo, Tsung Rong
N1 - Funding Information:
This research was funded by MOST 109-2113-M-038-005-MY2 and Taipei Medical University. We are greatly thankful to Chun-Chih Liu and Chi-Ming Lee for help with nanomaterial characterizations at the TMU Core Facility Center.
Publisher Copyright:
© 2021 American Chemical Society.
PY - 2021/6/14
Y1 - 2021/6/14
N2 - The metallic phase of 1T-MoS2 nanoflowers (NFs) and the semiconducting phase of 2H-MoS2 NFs were prepared by a facile solvothermal and combustion method. The antibacterial activities, reactive oxygen species (ROS) generation, and light-driven antibacterial mechanism of metallic 1T-MoS2 NFs and semiconducting 2H-MoS2 NFs were demonstrated with the bacterium Escherichia coli (E. coli) under light irradiation. Results of the bacterial growth curve and ROS generation analyses revealed higher light-driven antibacterial activity of metallic 1T-MoS2 NFs compared to semiconducting 2H-MoS2 NFs. Electron paramagnetic resonance (EPR) spectroscopy demonstrated that the ROS of the superoxide anion radical-O2- was generated due to the incubation of 1T-MoS2 NFs and E. coli with light irradiation. Furthermore, E. coli incubated with metallic 1T-MoS2 NFs exhibited significant damage to the bacterial cell walls, complete bacterial destruction, and abnormal elongation after light irradiation. The light-driven antibacterial mechanism of metallic 1T-MoS2 NFs was examined, and we found that, under light irradiation, photoinduced electrons were generated by metallic 1T-MoS2 NFs, and then the photoinduced electrons reacted with oxygen to generate superoxide anion radical which induced bacterial death. For semiconducting 2H-MoS2 NFs, photoinduced electrons and holes rapidly recombined resulting in a decrease in ROS generation which diminished the light-driven antibacterial activity.
AB - The metallic phase of 1T-MoS2 nanoflowers (NFs) and the semiconducting phase of 2H-MoS2 NFs were prepared by a facile solvothermal and combustion method. The antibacterial activities, reactive oxygen species (ROS) generation, and light-driven antibacterial mechanism of metallic 1T-MoS2 NFs and semiconducting 2H-MoS2 NFs were demonstrated with the bacterium Escherichia coli (E. coli) under light irradiation. Results of the bacterial growth curve and ROS generation analyses revealed higher light-driven antibacterial activity of metallic 1T-MoS2 NFs compared to semiconducting 2H-MoS2 NFs. Electron paramagnetic resonance (EPR) spectroscopy demonstrated that the ROS of the superoxide anion radical-O2- was generated due to the incubation of 1T-MoS2 NFs and E. coli with light irradiation. Furthermore, E. coli incubated with metallic 1T-MoS2 NFs exhibited significant damage to the bacterial cell walls, complete bacterial destruction, and abnormal elongation after light irradiation. The light-driven antibacterial mechanism of metallic 1T-MoS2 NFs was examined, and we found that, under light irradiation, photoinduced electrons were generated by metallic 1T-MoS2 NFs, and then the photoinduced electrons reacted with oxygen to generate superoxide anion radical which induced bacterial death. For semiconducting 2H-MoS2 NFs, photoinduced electrons and holes rapidly recombined resulting in a decrease in ROS generation which diminished the light-driven antibacterial activity.
KW - Metallic 1T-MoS
KW - Photoactivity
KW - Reactive oxygen species
KW - Semiconducting 2H-MoS
KW - Superoxide anion radical
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U2 - 10.1021/acssuschemeng.1c01868
DO - 10.1021/acssuschemeng.1c01868
M3 - Article
AN - SCOPUS:85108520766
SN - 2168-0485
VL - 9
SP - 7904
EP - 7912
JO - ACS Sustainable Chemistry and Engineering
JF - ACS Sustainable Chemistry and Engineering
IS - 23
ER -
