TY - JOUR
T1 - Phase-Dependent 1T/2H-MoS2Nanosheets for Effective Photothermal Killing of Bacteria
AU - Mutalik, Chinmaya
AU - Okoro, Goodluck
AU - Chou, Hung Lung
AU - Lin, I. Hsin
AU - Yougbaré, Sibidou
AU - Chang, Che Chang
AU - Kuo, Tsung Rong
N1 - Funding Information:
This work was financially supported by MOST 109-2113-M-038-005-MY2, TMU-NTUST-110-03, Taipei Medical University, and National Taiwan University of Science and Technology. We are grateful to the NCHC and NTUST for computer time and facilities. We would like to acknowledge Chun-Chih Liu and Dr. Chi-Ming Lee for their distinguished technical support at the TMU Core Facility Center.
Publisher Copyright:
© 2022 American Chemical Society.
PY - 2022/7/11
Y1 - 2022/7/11
N2 - The crystal phase of a nanomaterial can affect its biochemical properties and, as a result, greatly influence its application performance. Transition metal dichalcogenides (TMDs), a group of nanomaterials with the ability to crystallize into distinct crystal phases, show distinct electronic structures which are believed to be material-dependent. Molybdenum disulfide (MoS2) can crystallize into distinct crystal phases of 1T and 2H, and in each of these phases, MoS2 shows completely different and distinct biochemical properties. Although several biochemical properties of MoS2 have been extensively reported, particularly its role as a potent antibacterial agent, exactly how the different crystal phases of MoS2 nanosheets (NSs) influence the nanomaterial's biochemical performance in the near-infrared (NIR)-I window still remains unknown. Herein, we show through detailed experiments and density functional theory (DFT) simulation of the NIR-based electronic structure-activity relationship of 1T- and 2H-MoS2 NSs exactly how these two distinct phases influence the antibacterial performance at each crystal phase and the different factors involved in this process. We also show how the coordination modes, atomic arrangements, and water adsorption energies of these two crystal phases greatly impact the nanomaterial's distinct phase properties. 1T-MoS2 NSs are metallic phases with a lower band gap and surface water adsorption energy, while 2H-MoS2 NSs are semiconducting phases; as a result, 1T-MoS2 NSs show superior absorbance in the NIR-I window and hence display a higher photothermal performance and excellent antibacterial effects compared to the semiconducting 2H-MoS2 NSs. Our work shows the factors responsible for the distinct antibacterial behaviors of MoS2 NSs in the two crystal phases. We believe that these findings can be employed in the tunable, effective, and stable nanofabrication of MoS2 NSs as either photothermal agents for cancer cell ablation or as antimicrobial agents.
AB - The crystal phase of a nanomaterial can affect its biochemical properties and, as a result, greatly influence its application performance. Transition metal dichalcogenides (TMDs), a group of nanomaterials with the ability to crystallize into distinct crystal phases, show distinct electronic structures which are believed to be material-dependent. Molybdenum disulfide (MoS2) can crystallize into distinct crystal phases of 1T and 2H, and in each of these phases, MoS2 shows completely different and distinct biochemical properties. Although several biochemical properties of MoS2 have been extensively reported, particularly its role as a potent antibacterial agent, exactly how the different crystal phases of MoS2 nanosheets (NSs) influence the nanomaterial's biochemical performance in the near-infrared (NIR)-I window still remains unknown. Herein, we show through detailed experiments and density functional theory (DFT) simulation of the NIR-based electronic structure-activity relationship of 1T- and 2H-MoS2 NSs exactly how these two distinct phases influence the antibacterial performance at each crystal phase and the different factors involved in this process. We also show how the coordination modes, atomic arrangements, and water adsorption energies of these two crystal phases greatly impact the nanomaterial's distinct phase properties. 1T-MoS2 NSs are metallic phases with a lower band gap and surface water adsorption energy, while 2H-MoS2 NSs are semiconducting phases; as a result, 1T-MoS2 NSs show superior absorbance in the NIR-I window and hence display a higher photothermal performance and excellent antibacterial effects compared to the semiconducting 2H-MoS2 NSs. Our work shows the factors responsible for the distinct antibacterial behaviors of MoS2 NSs in the two crystal phases. We believe that these findings can be employed in the tunable, effective, and stable nanofabrication of MoS2 NSs as either photothermal agents for cancer cell ablation or as antimicrobial agents.
KW - 1T-MoSnanosheet
KW - 2H-MoSnanosheet
KW - antibacterial agent
KW - crystal phase
KW - electronic structure
KW - near-infrared radiation
KW - photothermal performance
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U2 - 10.1021/acssuschemeng.2c02457
DO - 10.1021/acssuschemeng.2c02457
M3 - Article
AN - SCOPUS:85135211072
SN - 2168-0485
VL - 10
SP - 8949
EP - 8957
JO - ACS Sustainable Chemistry and Engineering
JF - ACS Sustainable Chemistry and Engineering
IS - 27
ER -