Peroxisomal localization of serine:pyruvate aminotransferase in human liver.

T. Noguchi, Y. Takada

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)


The distribution of L-serine:pyruvate aminotransferase (EC in human liver was examined by centrifugation in a sucrose density gradient. The enzyme was located only in the peroxisomes and in the soluble fraction. The peroxisomal and soluble enzymes were highly purified and characterized. The two enzyme preparations had nearly identical properties, suggesting that the soluble enzyme is from broken peroxisomes. The two enzyme preparations showed different properties from rat liver serine:pyruvate aminotransferase (Noguchi, T., Okuno, E., and Kido, R. (1976) Biochem. J. 159, 607-613).

Original languageEnglish
Pages (from-to)7598-7600
Number of pages3
JournalJournal of Biological Chemistry
Issue number21
Publication statusPublished - Nov 10 1978
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology


Dive into the research topics of 'Peroxisomal localization of serine:pyruvate aminotransferase in human liver.'. Together they form a unique fingerprint.

Cite this