TY - JOUR
T1 - Peroxisomal localization of serine:pyruvate aminotransferase in human liver.
AU - Noguchi, T.
AU - Takada, Y.
N1 - Copyright:
Medline is the source for the citation and abstract of this record.
PY - 1978/11/10
Y1 - 1978/11/10
N2 - The distribution of L-serine:pyruvate aminotransferase (EC 2.6.1.51) in human liver was examined by centrifugation in a sucrose density gradient. The enzyme was located only in the peroxisomes and in the soluble fraction. The peroxisomal and soluble enzymes were highly purified and characterized. The two enzyme preparations had nearly identical properties, suggesting that the soluble enzyme is from broken peroxisomes. The two enzyme preparations showed different properties from rat liver serine:pyruvate aminotransferase (Noguchi, T., Okuno, E., and Kido, R. (1976) Biochem. J. 159, 607-613).
AB - The distribution of L-serine:pyruvate aminotransferase (EC 2.6.1.51) in human liver was examined by centrifugation in a sucrose density gradient. The enzyme was located only in the peroxisomes and in the soluble fraction. The peroxisomal and soluble enzymes were highly purified and characterized. The two enzyme preparations had nearly identical properties, suggesting that the soluble enzyme is from broken peroxisomes. The two enzyme preparations showed different properties from rat liver serine:pyruvate aminotransferase (Noguchi, T., Okuno, E., and Kido, R. (1976) Biochem. J. 159, 607-613).
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M3 - Article
C2 - 701275
AN - SCOPUS:0018265529
SN - 0021-9258
VL - 253
SP - 7598
EP - 7600
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
IS - 21
ER -