Patient education: An efficient adjuvant therapy for hyperphosphatemia in hemodialysis patients

Chiao Yin Sun, Kuo Chuan Chang, Sue Hsien Chen, Chiz Tzung Chang, Mai Szu Wu

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Background. Hemodialysis and phosphate (P) binder therapy are the major methods to reduce the phosphate level in dialysis patients. However, dietary P restriction is necessary for adequate control. The successful dietary control is based on patient compliance. Patient education is the best method to assure the knowledge and drive of dietary control, which are the key features for patient compliance. The aim of the study is to investigate quantitatively the effect of patient education on serum P levels in hyperphosphatemic hemodialysis patients. Methods. We conducted a prospective self-control study. Fifty hemodialysis patients with a pre-dialysis serum P level greater than 6.0 mg/dL were studied. Intensified patient education was given. Serum P, calcium (Ca), and intact parathyroid hormone (iPTH) were evaluated before and one month after patient education. Results. Thirty-six (72%) patients had improved pre-dialysis P level (pre-education: 7.50 ± 1.33; post-education: 5.85 ± 1.20 mg/dL, p < 0.001) and Ca x P product (pre-education: 68.17 ± 12.70; post-education: 54.70 ± 11.87 mg2/dL2, p < 0.001). The effect lasted for at least three months. There is no significant change on calcium levels. The only predictor of a successful patient education is the iPTH level (improved: 348.8 ± 277.6; non-improved: 668.0 ± 674.1 ng/mL, p = 0.021). Conclusions. Patient education could be helpful and efficient in hyperphosphatemic control in dialysis patients. The patient education should be given before the serum iPTH level getting high.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalRenal Failure
Issue number1
Publication statusPublished - Jan 2008
Externally publishedYes


  • Dialysis
  • Hyperphosphatemia
  • Patient education

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Nephrology


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