p38 MAPK activation and mitochondrial depolarization mediate the cytotoxicity of Taiwan cobra phospholipase A₂ on human neuroblastoma SK-N-SH cells

Medicine and Dentistry

• p38 Mitogen-Activated Protein Kinase 100%
• Phospholipase A2 100%
• Ganglioneuroblastoma 100%
• Cytotoxicity 100%
• 4 Bromophenacyl Bromide 30%
• Cell Death 20%
• Cell Viability 20%
• Tretinoin 20%
• Cytochrome C 20%
• Enzyme Activity 10%
• 4 (4 Fluorophenyl) 2 (4 Hydroxyphenyl) 5 (4 Pyridyl)imidazole 10%
• Mitochondrion 10%
• Mitochondrial Membrane Potential 10%
• Cyclosporine 10%
• Secretory Phospholipase A2 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytotoxicity 100%
• Naja Atra 100%
• Phospholipase A2 100%
• Neuroblastoma 100%
• 4 Bromophenacyl Bromide 30%
• Cell Viability 20%
• Cytochrome C 20%
• 4 (4 Fluorophenyl) 2 (4 Hydroxyphenyl) 5 (4 Pyridyl)imidazole 10%
• Ciclosporin 10%
• Secretory Phospholipase A2 10%

Biochemistry, Genetics and Molecular Biology

• P38 Mitogen-Activated Protein Kinases 100%
• Naja Atra 100%
• Cytotoxicity 100%
• Phospholipase A2 100%
• Cytochrome 18%
• Cell Viability 18%
• Cell Death 18%
• Mitochondrial Membrane Potential 9%
• Mitochondrion 9%
• Enzyme Activity 9%
• Ciclosporin 9%