TY - JOUR
T1 - Outcomes after surgery in patients with and without recent influenza
T2 - a nationwide population-based study
AU - Lam, Fai
AU - Liao, Chien Chang
AU - Chen, Ta Liang
AU - Huang, Yu Min
AU - Lee, Yuarn Jang
AU - Chiou, Hung Yi
N1 - Funding Information:
This study was supported in part by the Ministry of Science and Technology, Taiwan (MOST111-2320-B-532 -001-MY3; MOST110-2314-B-038-108-MY2; MOST108-2320-B-038-070-MY3).
Funding Information:
This study is based in part on data obtained from the National Health Insurance Research Database. This database was provided by the National Health Insurance Administration of Taiwan’s Ministry of Health and Welfare and is managed by the National Health Research Institutes. The authors’ interpretations and conclusions do not represent those of these agencies.
Publisher Copyright:
Copyright © 2023 Lam, Liao, Chen, Huang, Lee and Chiou.
PY - 2023
Y1 - 2023
N2 - Background: The influence of recent influenza infection on perioperative outcomes is not completely understood. Method: Using Taiwan’s National Health Insurance Research Data from 2008 to 2013, we conducted a surgical cohort study, which included 20,544 matched patients with a recent history of influenza and 10,272 matched patients without. The main outcomes were postoperative complications and mortality. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) for the complications and for mortality in patients with a history of influenza within 1–14 days or 15–30 days compared with non-influenza controls. Results: Compared with patients who had no influenza, patients with influenza within preoperative days 1–7 had increased risks of postoperative pneumonia (OR 2.22, 95% CI 1.81–2.73), septicemia (OR 1.98, 95% CI 1.70–2.31), acute renal failure (OR 2.10, 95% CI 1.47–3.00), and urinary tract infection (OR 1.45, 95% CI 1.23–1.70). An increased risk of intensive care admission, prolonged length of stay, and higher medical expenditure was noted in patients with history of influenza within 1–14 days. Conclusion: We found that there was an association between influenza within 14 days preoperatively and the increased risk of postoperative complications, particularly with the occurrence of influenza within 7 days prior to surgery.
AB - Background: The influence of recent influenza infection on perioperative outcomes is not completely understood. Method: Using Taiwan’s National Health Insurance Research Data from 2008 to 2013, we conducted a surgical cohort study, which included 20,544 matched patients with a recent history of influenza and 10,272 matched patients without. The main outcomes were postoperative complications and mortality. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) for the complications and for mortality in patients with a history of influenza within 1–14 days or 15–30 days compared with non-influenza controls. Results: Compared with patients who had no influenza, patients with influenza within preoperative days 1–7 had increased risks of postoperative pneumonia (OR 2.22, 95% CI 1.81–2.73), septicemia (OR 1.98, 95% CI 1.70–2.31), acute renal failure (OR 2.10, 95% CI 1.47–3.00), and urinary tract infection (OR 1.45, 95% CI 1.23–1.70). An increased risk of intensive care admission, prolonged length of stay, and higher medical expenditure was noted in patients with history of influenza within 1–14 days. Conclusion: We found that there was an association between influenza within 14 days preoperatively and the increased risk of postoperative complications, particularly with the occurrence of influenza within 7 days prior to surgery.
KW - infectious diseases
KW - influenza
KW - mortality
KW - perioperative outcomes
KW - surgery
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U2 - 10.3389/fmed.2023.1117885
DO - 10.3389/fmed.2023.1117885
M3 - Article
AN - SCOPUS:85163618372
SN - 2296-858X
VL - 10
JO - Frontiers in Medicine
JF - Frontiers in Medicine
M1 - 1117885
ER -