Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells

Agriculture & Biology

• AMP-activated protein kinase 79%
• myocytes 57%
• skeletal muscle 52%
• uptake mechanisms 38%
• glucose 34%
• glucose transporters 18%
• diabetes 15%
• plasma membrane 11%
• streptozotocin 9%
• noninsulin-dependent diabetes mellitus 9%
• acetyl-CoA carboxylase 8%
• insulin resistance 8%
• hyperglycemia 8%
• hypoglycemic agents 8%
• herbal medicines 8%
• blood lipids 7%
• adipose tissue 7%
• phosphorylation 6%
• Western blotting 6%
• energy 4%
• liver 4%
• metabolism 4%
• mice 4%
• lipids 3%
• dosage 3%

Medicine & Life Sciences

• osthol 96%
• AMP-Activated Protein Kinases 68%
• Muscle Cells 52%
• Skeletal Muscle 45%
• Glucose 36%
• Adenosine Monophosphate 11%
• Adenosine Triphosphate 8%
• Cell Membrane 7%
• Acetyl-CoA Carboxylase 7%
• Membrane Transport Proteins 6%
• Experimental Diabetes Mellitus 6%
• Herbal Medicine 5%
• Protein Kinase Inhibitors 5%
• Hypoglycemic Agents 4%
• Hyperglycemia 4%
• Adipose Tissue 4%
• Insulin Resistance 4%
• Type 2 Diabetes Mellitus 3%
• Fats 3%
• Phosphorylation 3%
• Western Blotting 3%
• Lipids 3%
• Muscles 3%
• Liver 2%

Chemical Compounds

• Osthole 100%
• Glucose 42%
• Protein 23%
• Plasma 10%
• Protein Kinase Inhibitor 8%
• Acetyl-CoA 7%
• Antidiabetic Agent 7%
• Insulin Derivative 5%
• Fat 5%
• Metabolic 4%
• Pharmacological Metabolism 4%
• Lipid 3%
• Energy 2%