Optimization of drug cocktail on an integrated microfluidic system

Wen Yen Huang; Kuan Wang; Gwo Bin Lee

doi:10.1109/MEMSYS.2015.7051043

Optimization of drug cocktail on an integrated microfluidic system

Wen Yen Huang
, Kuan Wang
, Gwo Bin Lee

Research output: Contribution to journal › Conference article › peer-review

1 Citation (Scopus)

Abstract

Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

Original language	English
Article number	7051043
Pages (from-to)	658-661
Number of pages	4
Journal	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2015-February
Issue number	February
DOIs	https://doi.org/10.1109/MEMSYS.2015.7051043
Publication status	Published - Feb 26 2015
Externally published	Yes
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2015.7051043

Cite this

@article{0dc644b7b35547678e29100a3ab685ab,

title = "Optimization of drug cocktail on an integrated microfluidic system",

abstract = "Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.",

author = "Huang, \{Wen Yen\} and Kuan Wang and Lee, \{Gwo Bin\}",

note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 ; Conference date: 18-01-2015 Through 22-01-2015",

year = "2015",

month = feb,

day = "26",

doi = "10.1109/MEMSYS.2015.7051043",

language = "English",

volume = "2015-February",

pages = "658--661",

journal = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

issn = "1084-6999",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

number = "February",

}

TY - JOUR

T1 - Optimization of drug cocktail on an integrated microfluidic system

AU - Huang, Wen Yen

AU - Wang, Kuan

AU - Lee, Gwo Bin

PY - 2015/2/26

Y1 - 2015/2/26

N2 - Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

AB - Optimization of drug cocktails has been an important issue for a number of therapies of complicated diseases; however, it is an extremely task using traditional methods. Here we demonstrate a new microfluidic platform capable of automatically dispensing, mixing a small amount of drug combinations, and adding them to the cell cultures such that a precise and fine-tuned drug cocktails may be formed for the subsequent cell-level testing. Our proposed system could decrease manual bias and enhance the throughput of drug cocktail formulation on an automated and minituriazed microfluidic system.

UR - https://www.scopus.com/pages/publications/84931091939

UR - https://www.scopus.com/pages/publications/84931091939#tab=citedBy

U2 - 10.1109/MEMSYS.2015.7051043

DO - 10.1109/MEMSYS.2015.7051043

M3 - Conference article

AN - SCOPUS:84931091939

SN - 1084-6999

VL - 2015-February

SP - 658

EP - 661

JO - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

JF - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

IS - February

M1 - 7051043

T2 - 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015

Y2 - 18 January 2015 through 22 January 2015

ER -

Optimization of drug cocktail on an integrated microfluidic system

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this